ArticleFrontiers in cardiovascular medicine2026
Effect of remote ischemic preconditioning on the risk of contrast-induced acute kidney injury in patients with coronary heart disease undergoing percutaneous coronary intervention.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contrast-induced acute kidney injury (CIAKI) is a frequent and clinically important complication after percutaneous coronary intervention (PCI). Despite standard preventive strategies including adequate hydration and the use of low- or iso-osmolar contrast media, the residual risk of CIAKI remains substantial. Remote ischemic preconditioning (RIPC), a non-invasive method involving brief cycles of ischemia and reperfusion applied to a limb, has been proposed as a potential strategy to mitigate ischemia-reperfusion injury, including in the kidneys. However, the impact of RIPC on the incidence of CIAKI after PCI in patients with CHD remains unclear. This study aim is to investigate the impact of RIPC on the incidence of CIAKI in patients with CHD undergoing PCI. A total of 484 patients who underwent elective PCI were enrolled and randomly assigned to either the RIPC or control group. The RIPC group received preconditioning twice daily for two days prior to PCI and once again two hours before the procedure. Renal function was assessed at baseline, 48 h, and one week post-PCI. The primary endpoint was the incidence of CIAKI, and the secondary endpoint was the occurrence of major adverse cardiac events (MACE) during the 90-day follow-up. Results showed that the incidence of CIAKI was significantly lower in the RIPC group compared to the control group (6.2% vs. 12.0%,
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.