ArticleFrontiers in public health2026
Potential profiles and associated factors of medication safety competence at home: a study in the older adults following percutaneous coronary intervention.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To explore the latent profiles of home medication safety competence in older adults patients after percutaneous coronary intervention (PCI) and analyze the associated factors of different latent profiles, so as to provide a reference for constructing precise medication management plans. Methods: Convenience sampling was used to select older adults patients who underwent PCI in the Department of Cardiology of a tertiary general hospital in Sichuan Province from February to June 2025 as the study subjects. General information questionnaire, Medication Safety Competence Scale, Short Health Literacy Scale, and Family APGAR Scale were used for investigation. Latent profile analysis was used to identify profiles of medication safety competence. We compared 1 to 4 profiles and chose the best model based on fit indices [Akaike information criterion (AIC), Bayesian information criterion (BIC), adjusted Bayesian information criterion (aBIC)], entropy, and interpretability. Multivariate logistic regression was used to analyze the associated factors. Results: A total of 393 older adults patients after PCI were included, with an average score of home medication safety competence of (102.081 ± 6.11) points. A 3-profile model was selected as the best solution (AIC = 8,837.83, BIC = 8,909.36, entropy = 0.875). Three profiles were identified: low competence group (31.0%), moderate competence group (56.0%), and high competence group (13.0%). Education level, age, health literacy, family support, and family medication reminder frequency were the main factors associated with patients' belonging to different competence profiles (all Conclusion: There is significant population heterogeneity in home medication safety competence among older adults patients after PCI. In nursing practice, stratified and precise intervention strategies should be adopted based on the characteristics and associated factors of different competence profiles. Special attention should be paid to patients with low education level, advanced age, low health literacy, and weak family support. Enhancing patients' health literacy and strengthening the family support system are essential to promote and maintain their home medication safety competence.
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