Evidence map›Paper›PMID 42369035›Full record

ArticleiScience2026

Multiomics reveals fatty acid metabolism and immune remodeling in retinal artery occlusion.

Jiaqing Feng, Duan Chen, Chuansen Wang, Runlang Zhu, Longfei Chen, Liang Hu, Ting Chen, Ying Li, Xuan Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaqing FengDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Duan ChenDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Chuansen WangDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Runlang ZhuDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Longfei ChenDepartment of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Liang HuDepartment of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Ting ChenDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Ying LiDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Xuan XiaoDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal artery occlusion (RAO), an acute ocular ischemic stroke, is critically linked to cardiovascular and metabolic dysfunction. To elucidate the interplay between lipid metabolism and immune regulation in RAO, we performed an integrated analysis using serum metabolomics, PBMC transcriptomics, and machine learning in 66 patients with RAO and 66 cataract controls. We identified systemic disruptions in fatty acid metabolism, notably elevated levels of long-chain fatty acids (C22:5

Indexed as

biological sciences

Identifiers

PMID42369035
PMCPMC13293730

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.