ArticleFrontiers in medicine2026
The impact of self-management ability on oral frailty in older adults with hypertension: the chain mediating role of anxiety and nutritional status.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The incidence of oral frailty among older hypertensive adults is as high as 61.5%, which is mainly characterized by impairments in oral functions such as chewing and speech, which in turn increases the risk of adverse outcomes, and mortality. Previous studies have shown that hypertension self-management ability, anxiety, and nutritional status are influencing factors of oral frailty, yet the mechanisms underlying their interactions remain unclear. Methods: This study adopted a cross-sectional survey design. Using convenience sampling, 740 inpatients with hypertension were recruited from five medical institutions in Jiangsu Province. Data were collected through structured face-to-face interviews using the following scales: Self-Management Scale for Patients with Hypertension (SMSPH), Generalized Anxiety Disorder 7-item Scale (GAD-7), Short-Form Mini-Nutritional Assessment (MNA-SF), and Oral Frailty Index-8 (OFI-8). Spearman's correlation analysis was used to test the pairwise correlations among variables, and structural equation modeling (SEM) was employed to analyze mediating effects. Results: There were significant pairwise correlations between hypertension self-management ability, oral frailty, anxiety, and nutritional status ( Conclusion: Anxiety and nutritional status play mediating roles in the relationship between hypertension self-management ability and oral frailty in older hypertensive adults, with a serial mediating effect of anxiety-nutritional status. Clinicians could implement comprehensive intervention measures to improve patients' self-management ability, alleviate anxiety, and optimize nutritional status, thereby preventing and controlling oral frailty.
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