SynthesisFrontiers in medicine2026
Does intraoperative anesthesia handovers associated with adverse outcomes? A systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
3 authors.
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Abstract
Background: Intraoperative anesthesia handover is a common occurrence; however, limited research has explored its impact on patient outcomes. The purpose of this systematic review and meta-analysis was to assess the effects of anesthesia handovers on adverse outcomes in surgical settings. Methods: All clinical studies that specifically investigated the association between anesthesia handovers and adverse patient outcomes were included. The MEDLINE, Cochrane Library trials, PubMed, Embase, and Web of Science databases were searched from inception to June 15, 2025. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS). Using STATA and R statistical software, exploratory and cumulative meta-analyses were conducted using a random-effects model for adjusted ratio risks (aRR) with 95% confidence intervals [95% CI]. Subgroup and sensitivity analyses were also performed given potential heterogeneity. Results: Meta-analyses of 14 studies revealed a significant association between anesthesia handovers and several adverse outcomes, including composite in-hospital mortality and morbidity (aRR = 1.44, 95% CI 1.23-1.69, I Conclusions: Intraoperative anesthesia handovers are generally associated with an increased risk of mortality and morbidity in surgical patients. Future research should prioritize identifying the specific characteristics of anesthesia handovers that affect patient safety. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier: CRD420251140062.
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