SynthesisFrontiers in physiology2026
Efficacy of different exercise modalities for sleep quality in Parkinson's disease: a systematic review and network meta-analysis.
Synthesis in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Background: Sleep disturbances are a common and burdensome non-motor symptom in Parkinson's disease (PD). The comparative efficacy of different exercise modalities for sleep quality in PD remains unclear. This network meta-analysis (NMA) aimed to compare and rank the effects of various exercise interventions on sleep quality in people with PD. Methods: This study followed the PRISMA extension statement for network meta-analyses. A systematic search was performed across Web of Science, Embase, PubMed, the Cochrane Library, Scopus, CNKI, and Wanfang databases from their inception to November 3, 2025. Eligible randomized controlled trials (RCTs) were identified, with study selection, data extraction, and bias assessment conducted independently by two reviewers. NMA was performed using Stata 19.0. Consistency was examined using design-by-treatment interaction and node-splitting approaches. Rankings were estimated using the surface under the cumulative ranking curve (SUCRA). Results: Of 2309 records screened, 16 RCTs involving 932 people with PD were included. Aerobic exercise (AE) significantly improved sleep quality compared with control (SMD = -0.94, 95% CI: -1.82 to -0.07). SUCRA rankings were: AE (highest) > multimodal exercise (MME) > resistance training (RT) > stretching training (ST) > mind-body exercise (MBE) > control. No significant publication bias was found (Egger's test, P = 0.438). Conclusion: This NMA indicates that aerobic exercise is the most promising modality for enhancing sleep quality in people with PD and may guide non-pharmacological treatment selection in clinical practice. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420261341953.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.