ReviewEULAR rheumatology open2026
Fertility and pregnancy outcomes after CAR T-cell therapy: insights from a systematic review.
Review in EULAR rheumatology open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chimeric antigen receptor (CAR) T-cell therapy represents an emerging option for refractory autoimmune diseases, but long-term effects are unknown. Based on its remarkable effects in achieving drug-free remission in highly selected patients, a possible role in the early disease course is also discussed. With the increasing use of this treatment in patients of reproductive age, understanding its impact on fertility and pregnancy is crucial to provide counselling. Evidence from oncology provides valuable insights for rheumatology. We found 3 publications reporting 10 pregnancies after CAR T-cell therapy of the mother (
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.