Evidence mapPaperPMID 42370515Full record

ArticleCartilage2026

Sex and Age Affect Progression to Total Knee Arthroplasty After Cartilage Surgery: A UK Biobank Cohort Study.

Nicola J Kuiper, Charlotte H Hulme, Martyn Snow, Martin Frisher, Karina T Wright, Jan Herman Kuiper

Abstract read
In one paragraph

Article in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicola J KuiperOswestry/Keele Orthopaedic Research Group, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, UK.ORCID 0000-0001-6173-1446
Charlotte H HulmeOswestry/Keele Orthopaedic Research Group, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, UK.ORCID 0000-0002-4961-2185
Martyn SnowOswestry/Keele Orthopaedic Research Group, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, UK.ORCID 0000-0002-1366-109X
Martin FrisherSchool of Allied Health Professions & Pharmacy, Keele University, UK.
Karina T WrightOswestry/Keele Orthopaedic Research Group, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, UK.ORCID 0000-0001-8842-5908
Jan Herman KuiperOswestry/Keele Orthopaedic Research Group, The Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, UK.ORCID 0000-0002-7023-4078

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveEvaluate the association of sex and age at surgery with time to total knee arthroplasty (TKA) following knee cartilage surgery in UK Biobank (UKB) participants.DesignParticipants with a history of knee cartilage surgery were classified into four surgical subgroups: cartilage repair, debridement, microfracture, and unicompartmental knee arthroplasty. Time from index surgery to primary TKA in each group was analysed using the Kaplan-Meier method and the sexes compared using log-rank tests. Cox proportional hazards regression evaluated associations between age at surgery, sex, and surgery type with risk of progression to TKA.ResultsThe study included 1,967 males and 1,741 females. Log‑rank testing demonstrated significant sex‑based differences in time to TKA following debridement (

Indexed as

articular cartilagecartilage lesionscartilage repairdebridementmicrofracturesex differencestotal knee arthroplastyunicompartmental arthroplasty

Identifiers

PMID42370515
PMCPMC13314653

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.