Evidence map›Paper›PMID 42371573›Full record

ArticleFrontiers in surgery2026

Beyond BMI: L4-L5 visceral-to-subcutaneous fat ratio on CT predicts impaired wound healing after posterior lumbar fusion-A retrospective study.

Jinwang Liu, Xiaoping Xu, Shaoxing Li, Hua Yu

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Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jinwang Liu *Department of Orthopedics, The First Affiliated Hospital of Chengdu Medical College, Sichuan, China.
Xiaoping Xu *Department of Orthopedics, The First Affiliated Hospital of Chengdu Medical College, Sichuan, China.
Shaoxing LiDepartment of Gynaecology and Obstetrics, The First Affiliated Hospital of Chengdu Medical College, Sichuan, China.
Hua YuDepartment of Orthopedics, The First Affiliated Hospital of Chengdu Medical College, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity is a recognized risk factor for postoperative complications after spine surgery, but body mass index (BMI) does not capture regional fat distribution. The visceral-to-subcutaneous fat area (VFA/SFA) ratio measured on CT reflects an unfavorable fat distribution pattern, yet its role in wound healing after posterior lumbar fusion (PLF) is unclear. Methods: We retrospectively analyzed 526 adults who underwent instrumented PLF for degenerative lumbar pathology and had preoperative non-contrast abdominal CT including the L4-L5 level. On a single axial slice at L4-L5, visceral fat area (VFA) and subcutaneous fat area (SFA) were segmented using a semi-automated protocol and the VFA/SFA ratio was calculated and grouped into quartiles. The primary outcome was impaired wound healing within 30 days, defined as persistent erythema or swelling, fat liquefaction, prolonged serous/serosanguinous exudation, partial wound edge necrosis or superficial dehiscence, or the need for negative-pressure therapy, delayed suture removal, additional antibiotics, or surgical debridement. Group comparisons used t tests and Results: Impaired wound healing occurred in 59 patients (11.2%). Compared with patients with good healing, those with impaired wound healing had higher BMI (25.4 ± 4.0 vs. 23.1 ± 3.8 kg/m Conclusion: The preoperative VFA/SFA ratio at L4-L5 is an independent predictor of impaired wound healing after PLF and provides incremental discriminative value beyond BMI and conventional clinical risk factors.

Indexed as

posterior lumbar fusionsubcutaneous fat areasurgical site complicationsVFA/SFA ratiovisceral fat area

Identifiers

PMID42371573
PMCPMC13310561

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.