Evidence map›Paper›PMID 42373222›Full record

ArticleCancer genomics & proteomics

Genetic Insights into Interleukin-13 Polymorphisms in Colorectal Cancer Risk and Progression.

Te-Cheng Yueh, Tao-Wei Ke, Jiaqi Wang, Yang Deng, Yi-Chih Hung, Cheng-Wei Huang, Yu-Chen Chang, Chia-Wen Tsai, Wen-Shin Chang, Jian Gu and 1 more

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Article in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Te-Cheng Yueh *National Defense Medical University, Taipei, Taiwan, R.O.C.
Tao-Wei Ke *Department of Colorectal Surgery, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Jiaqi Wang *Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, U.S.A.
Yang DengDepartment of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China.
Yi-Chih HungTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Cheng-Wei HuangDepartment of Colorectal Surgery, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Yu-Chen ChangDepartment of Colorectal Surgery, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chia-Wen TsaiDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, U.S.A.
Wen-Shin ChangDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, U.S.A.
Jian GuDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, U.S.A.; jiangu@mdanderson.org 013280@tool.caaumed.org.tw.
DA-Tian BauTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; jiangu@mdanderson.org 013280@tool.caaumed.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimColorectal cancer (CRC) is a major global health burden with increasing incidence and significant mortality, particularly in advanced stages. Genetic susceptibility and inflammation-related pathways, including cytokine signaling, are increasingly recognized as key contributors to CRC pathogenesis. Interleukin-13 (IL-13) polymorphisms, particularly rs1800925 and rs20541, have been implicated in cancer biology; however, their roles in CRC remain inconclusive. MATERIALS AND

methodsA hospital-based case-control study was conducted in Taiwan, including 362 CRC patients and 362 age- and sex-matched controls. Genomic DNA was extracted from peripheral blood, and

resultsThe genotype distributions of rs1800925 and rs20541 in controls conformed to the Hardy-Weinberg equilibrium (

conclusionAlthough

Indexed as

Colorectal NeoplasmsGenetic Predisposition to DiseaseInterleukin-13Polymorphism, Single NucleotideAgedCase-Control StudiesDisease ProgressionFemaleGenotypeHumansMaleMiddle AgedRisk FactorsTaiwanIL13 protein, humanInterleukin-13Colorectal cancergenotypeinterleukin-13metastasispolymorphismstage

Identifiers

PMID42373222
PMCPMC13321704

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.