Evidence map›Paper›PMID 42373974›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2026

From molecular mechanisms to digital surveillance: the 2010-2025 evolution of benzodiazepine and Z-drug misuse research.

Jianxi Liu, Weitao Zhu, Zilong Zhang, Quan Zhao, Yinglin Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jianxi LiuCollaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugsin, Key Laboratory of Molecular Pharmacology andDrug Evaluation, Ministry of Education, School of Pharmacy, Universities of Shandong, Yantai University, Yantai, 264005, People's Republic of China.
Weitao ZhuSchool of Pharmacy, Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Shandong Medical and Pharmaceutical University, Yantai, 264003, People's Republic of China.
Zilong ZhangCollaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugsin, Key Laboratory of Molecular Pharmacology andDrug Evaluation, Ministry of Education, School of Pharmacy, Universities of Shandong, Yantai University, Yantai, 264005, People's Republic of China.
Quan ZhaoDepartment of Pharmacy, Shandong Province, Yantai Yuhuangding Hospital, Yantai, 264000, People's Republic of China. zhaoquan_1419@163.com.
Yinglin WangDepartment of Pharmacy, Shandong Province, Yantai Yuhuangding Hospital, Yantai, 264000, People's Republic of China. wyl-sd@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The misuse of benzodiazepines (BZDs) and Z-drugs poses significant global public health challenges. This study maps the scientific evolution and paradigm shifts in this field from 2010 to 2025. A bibliometric analysis of 6,311 publications from the Web of Science Core Collection was performed using VOSviewer and CiteSpace to identify collaboration networks, research hotspots, and emerging frontiers. The USA and Harvard Medical School dominated global contributions. Research hotspots evolved through three distinct phases: (1) 2010-2014 focused on GABA

Indexed as

BenzodiazepinesDesigner DrugsSubstance-Related DisordersAnimalsHumansBenzodiazepinesDesigner DrugsBenzodiazepine misuseBibliometric analysisDesigner benzodiazepinesDigital surveillanceGABAA receptor subtypesPharmacodynamic synergy

Identifiers

PMID42373974

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.