Trial reportBMC anesthesiology2026
Effect of ultrasound-guided thyroid cartilage plane block on postoperative sore throat in patients undergoing vocal cord polypectomy under suspension laryngoscopy: a randomized controlled trial.
Trial report in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
7 authors.
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Abstract
objectiveTo evaluate the efficacy of ultrasound-guided thyroid cartilage plane block (TCPB) on postoperative sore throat (POST) in patients undergoing suspension laryngoscopy vocal cord polypectomy (SLVCP).
methodsNinety patients scheduled for elective SLVCP were randomized to either the TCPB group (general anesthesia + ultrasound-guided TCPB) or the C group (conventional GA), with 45 patients in each. The primary outcome was the incidence of POST at 2 h after extubation. Secondary outcomes included the incidence and severity of POST at 0.5, 2, 6, 12, and 24 h after extubation; the incidence and severity of hoarseness at 0.5, 2, 6, 12, and 24 h after extubation; and cough response during emergence.
resultsThe incidence of POST was significantly higher in the C group compared to the TCPB group at 0.5 h (93% vs. 67%, RR = 0.20, 95% CI [0.06-0.64]; P = 0.003), 2 h (78% vs. 47%, RR = 0.42, 95% CI [0.23-0.77]; P = 0.004), and 6 h (64% vs. 27%, RR = 0.49, 95% CI [0.32-0.77]; P = 0.001) after extubation. No significant difference in the incidence and severity of hoarseness between the groups at any time point. During extubation, the incidence of cough response in the C group was 60%, significantly higher than the 20% in the TCPB group (RR = 0.50, 95% CI [0.34-0.74]; P = 0.001).
conclusionUltrasound-guided TCPB significantly reduces the incidence and severity of POST and cough response in SLVCP patients.
trial registrationThis trial was registered in the Chinese Clinical Trial Registry (ChiCTR2500100227) on April 7, 2025 ( https://www.chictr.org.cn/ ).
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