Evidence map›Paper›PMID 42374423›Full record

ArticleMalaria journal2026

Malaria among febrile patients during a yellow fever outbreak in Ghana: a cross-sectional study.

Lidiwan Mensah, Anisa Abdulai, Gloria Amegatcher, Deborah Pratt, Evans Aduhene, Magdalene Sarah Nketia Ofori, Abdul Rahim Mohammed Sabtiu, Patience Lartekai Adams, Prince Ketorwoley, Christopher Mfum Owusu-Asenso and 4 more

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Article in Malaria journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Lidiwan MensahCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Anisa AbdulaiCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Gloria AmegatcherDepartment of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, Ghana.
Deborah PrattDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
Evans AduheneCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Magdalene Sarah Nketia OforiDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
Abdul Rahim Mohammed SabtiuCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Patience Lartekai AdamsDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
Prince KetorwoleyDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
Christopher Mfum Owusu-AsensoCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Nana Aba Setorwu EyesonCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Kwamena William Coleman SagoeCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Joseph Humphrey Kofi BonneyDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana. kbonney@noguchi.ug.edu.gh.
Yaw Asare AfraneCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana. yafrane@ug.edu.gh.

Funding

Regional Centre for Vector Borne Diseases in West Africa (RCVBD)D43TW011513 · FIC · UNIVERSITY OF GHANA · PI YAW ASARE AFRANE, Guiyun Yan · 2021 to 2026
$1.5M
FIC NIH HHS D43 TW011513NIH HHS D43 TW 011513
6 · The paper itself

Abstract

introductionBetween October 2021 and February 2022, there was an outbreak of yellow fever viral disease that spread within several districts in the northern part of Ghana. Malaria is the leading cause of death in most sub-Saharan countries including Ghana. It is important that surveillance is focused on malaria among febrile patients during a yellow fever outbreak in Ghana. This study investigated infection with malaria among febrile patients during a yellow fever outbreak in Ghana.

methodsThe study was a cross-sectional study conducted in two yellow fever outbreak sites (Wenchi and Damongo) and two non-outbreak sites (Kumbungu and Tamale). A total of 498 febrile patients from healthcare facilities were recruited in the rainy and dry seasons. A structured questionnaire was administered to collect patients' demographic information. Venous blood was collected from consented study participants for malaria parasite detection via microscopy and nested Polymerase Chain Reaction (PCR). Total RNA was extracted from serum samples for the detection of yellow fever virus using Reverse Transcription-PCR (RT-PCR).

resultsNone of the patients tested positive for yellow fever virus by RT-PCR. Out of a total of 498 febrile participants, 129/498 (25.90%) tested positive by PCR for P. falciparum parasites and 378 were examined for malaria microscopy with 54/378 (14.29%) testing positive to P. falciparum parasite detection. While there were 54/410 (13.17%) cases of P. falciparum infections via microscopy in the rainy season there was no positive infection in the dry season 0/88 (0%). However, the difference in malaria prevalence via PCR in the rainy and dry seasons was not significant (P > 0.05).

conclusionNucleic acid for yellow fever was not detected among all the febrile patients. High malaria prevalence was found in participants in the study sites, affecting preschool and the school-aged children the most. This suggests an underscoring urgent need for malaria interventions to mitigate high transmission within communities especially among school-based populations.

Indexed as

Disease OutbreaksFeverMalaria, FalciparumYellow FeverAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCross-Sectional StudiesFemaleGhanaHumansInfantMaleGhanaMalariaMicroscopyOutbreakPCRYellow fever

Identifiers

PMID42374423
PMCPMC13584243

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.