Evidence map›Paper›PMID 42375165›Full record

ArticlePreventive medicine reports2026

Combined effects of xylene and noise exposure at realistic low levels on hearing impairment: a cross-sectional study in China.

Zhihao Shi, Genyuan Li, Zhehua Zhou

Abstract read
In one paragraph

Article in Preventive medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhihao ShiJiaxing Center for Disease Control and Prevention, Jiaxing 314050, Zhejiang, China.
Genyuan LiJiaxing Center for Disease Control and Prevention, Jiaxing 314050, Zhejiang, China.
Zhehua ZhouJiaxing Center for Disease Control and Prevention, Jiaxing 314050, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate the combined effect of low-level xylene and noise exposure on hearing impairment in Chinese manufacturing workers and to provide evidence for occupational hearing protection strategies in China. Methods: A cross-sectional survey was conducted among 899 workers (295 co-exposed, 604 noise-only) in Jiaxing City, China from 2023 to 2025. Workplace noise and xylene concentrations were monitored, and pure-tone audiometry was performed with age-gender correction. Binary logistic regression and stratified regression analysis were used to evaluate risk factors for high-frequency hearing loss (HFHL). Results: The HFHL prevalence was 5.76% in the combined exposure group and 2.48% in the noise-only group ( Conclusions: Combined xylene and noise exposure exerts a significant synergistic ototoxic effect even when both exposures are within Chinese national occupational exposure limits.

Indexed as

Combined exposureHearing lossNoiseOrganic solventsSynergistic ototoxic effectXylene

Identifiers

PMID42375165
PMCPMC13311278

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.