Evidence map›Paper›PMID 42375846›Full record

ArticleFrontiers in cardiovascular medicine2026

Congestion, but not low cardiac output, is independently associated with acute kidney injury following contrast agent exposure.

Jean Marc Haurand, Elric Zweck, Patrick Horn, Christian Jung, Malte Kelm, Frank Ruschitzka, Ralf Westenfeld, Amin Polzin

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jean Marc HaurandDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Elric ZweckDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Patrick HornDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Christian JungDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Malte KelmDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Frank RuschitzkaDepartment of Cardiology, University Hospital Zurich, Zurich, Switzerland.
Ralf WestenfeldDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Amin PolzinDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Contrast-associated acute kidney injury (CA-AKI) is frequently associated with adverse outcomes. Renal perfusion gradient is central to glomerular filtration. While renal vasoconstriction can partially compensate low-output-associated impairment of the renal perfusion gradient, venous congestion cannot be compensated. We hypothesized that congestion is a stronger predictor of CA-AKI than low output in cardiovascular diseases. Methods and results: An all-comer single-center cohort of 3,126 cases undergoing coronary angiography with simultaneous right heart catheterization was analyzed. Patients were divided into four categories: congested [right atrial pressure (RAP) >10 mmHg and cardiac index (CI) >=2.2 L/min/m Conclusions: Venous congestion is independently associated with CA-AKI and is a stronger predictor of CA-AKI than low cardiac output.

Indexed as

acute kidney injurybackward failureforward failurelow outputMEHRAN scorevenous congestion

Identifiers

PMID42375846
PMCPMC13311108

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.