ArticleOpen veterinary journal2026
Immunomodulatory effects of oregano extract ointment on the expression of IL-10 and VEGF in white rat excision wounds.
Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Wound healing involves a sequential transition from inflammation to proliferation, requiring a balanced immune response. The disruption of this balance can impair repair. Aim: This study aimed to evaluate the effect of topical oregano extract ointment on the expression of IL-10 and VEGF in a rat excisional wound model. Methods: Twenty-four male white rats were randomly assigned to four groups ( Results: IL-10 expression showed an upward trend in the oregano-treated groups compared with the vehicle control; however, the differences did not reach statistical significance. In contrast, VEGF expression was significantly increased in the 6% oregano extract group compared with the vehicle control ( Conclusion: Oregano extract modulated the expression of molecular markers associated with wound healing, with the 6% concentration significantly increasing VEGF expression. IL-10 showed a non-significant upward trend across the treatment groups. These results suggest that oregano extract may support pathways involved in tissue repair, with 6% representing a potentially optimal concentration under the conditions of this study.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.