ArticleOpen veterinary journal2026
Protective effect of young coconut water on MMP -1 levels and collagen fiber thickness in male Wistar rats exposed to UVB light exposure.
Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: Exposure to ultraviolet B (UVB) light plays a key role in photoaging by increasing oxidative stress, activating inflammatory pathways, and increasing the expression of matrix metalloproteinase-1 (MMP-1), which causes dermal collagen degradation. Young coconut water contains various bioactive compounds with antioxidant activity that can protect the skin from UVB-induced damage. Aim: This study aimed to analyze the effect of the oral administration of young coconut water on MMP-1 levels and collagen fiber thickness in male Wistar rats exposed to UVB light. Methods: A purely experimental study with a post-test only control group design was conducted on 24 male Wistar rats divided into four groups: healthy controls (K1), UVB exposure (K2), UVB + young coconut water 4 ml/200 g BW/day (K3), and UVB + young coconut water 8 ml/200 g BW/day (K4). UVB exposure was administered for 15 days at a cumulative dose of 800 mJ/cm². MMP-1 levels were measured using an enzyme-linked immunosorbent assay method, while collagen fiber thickness was analyzed using Masson's Trichrome staining. Results: UVB exposure significantly increased MMP-1 levels and decreased collagen fiber thickness ( Conclusion: Young coconut water has potential as a natural antioxidant agent that can inhibit the increase in MMP-1 and maintain collagen fiber thickness in the skin caused by UVB exposure, thus potentially being used in the prevention of photoaging.
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