ArticleOpen veterinary journal2026
Histochemical study of cingulin and CD34 in the skin of a stray Dog.
Article in Open veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Background: Cingulin (CGN) is a tight junction cytoplasmic plaque that regulates gene expression and signal transduction. CD34 is a stem cell that has the potential to achieve self-renewal, continuously producing functional cells to maintain the homeostasis of the epidermis. Aim: This study aimed to understand the distribution, expression, and composition of CGN and CD34 in the epidermal layer compartments of the skin of healthy stray dogs of various ages and to illustrate the relationships between CD34 and CGN. Methods: Twenty male and twenty female dogs were allocated into four groups. Group 1, aged between 6 months and 1 year. Group 2, dogs aged between 1 and 2 years; Group 3, dogs aged between 2 and 4 years; and Group 4, dogs aged between 4 and 6 years. Skin biopsy samples from healthy dogs were obtained from the face, back, and leg regions. Histomorphometric assessment Results: In male dogs, Groups 3 and 1 had the highest levels of apoptosis in the back region ( Conclusion: These findings propose a region-specific regenerative capacity, lowest in the facial skin, which could explain an increased risk for dermatitis on the face compared with other body locations.
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