ArticleOpen veterinary journal2025
Functional recovery from malnutrition via extracts of
Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Malnutrition, particularly protein-energy malnutrition (PEM), remains a global health concern. Functional foods sourced from crops such as Aim: This study evaluated the effects of Methods: Male Wistar rats were fed a low-protein diet for 14 days to induce PEM, followed by a 28-day oral treatment phase using EEG, MEB, or their combinations at graded doses. Bodyweight, hematological profiles, and serum iron levels were measured. Small intestine peptide transporter 1 (PEPT1) gene expression was analyzed by immunohistochemistry. Phytochemical content and antioxidant capacity (IC Results: All treatment groups showed improved weight gain, with the most significant effect observed in the high-dose combination group. Hematological parameters remained stable, and serum iron levels increased in all treated rats. PEPT1 expression was significantly upregulated, especially in the MEB and combination groups. MEB exhibited higher phenolic and flavonoid content and stronger antioxidant activity (IC Conclusion: EEG and MEB, individually or in combination, improved nutritional markers and enhanced nutrient transporter expression in malnourished rats. These results support their potential as functional food candidates for managing PEM.
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