Evidence mapPaperPMID 42377028Full record

ArticlemSystems2026

Signatures in the gut microbiome of German elite athletes: insights from a matched-subgroup analysis.

Claudia Lenz, Waldemar Seel, Theresa Dombrowski, Sebastian Hacker, Marie-Christine Simon, Karen Zentgraf, Christine Dawczynski, Karsten Krüger

Abstract read
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claudia Lenz *Department of Exercise Physiology and Sports Therapy, Justus-Liebig-Universität Gießen, Giessen, Germany.ORCID 0009-0002-8690-6526
Waldemar Seel *Nutrition and Microbiota, Institute of Nutrition and Food Sciences, University of Bonn, Bonn, Germany.ORCID 0009-0004-4443-9143
Theresa DombrowskiDepartment of Exercise Physiology and Sports Therapy, Justus-Liebig-Universität Gießen, Giessen, Germany.
Sebastian HackerDepartment of Exercise Physiology and Sports Therapy, Justus-Liebig-Universität Gießen, Giessen, Germany.ORCID 0000-0003-1324-9510
Marie-Christine SimonNutrition and Microbiota, Institute of Nutrition and Food Sciences, University of Bonn, Bonn, Germany.ORCID 0000-0001-6625-1265
Karen ZentgrafDepartment of Movement and Exercise Science, Goethe-Universität Frankfurt, Frankfurt, Germany.ORCID 0000-0002-1118-4015
Christine Dawczynski *Junior Research Group Nutritional Concepts, Institute of Nutrition, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-4063-6199
Karsten Krüger *Department of Exercise Physiology and Sports Therapy, Justus-Liebig-Universität Gießen, Giessen, Germany.ORCID 0000-0003-1506-8254

Funding

Bundesinstitut für Sportwissenschaft (BISp) 081901/21-25Bundesministerium für Bildung und Forschung (BMBF) 01EA1707 & 01EA1708Deutsche Forschungsgemeinschaft (DFG) EXC2151-390873048
6 · The paper itself

Abstract

Elite athletes undergo intense physical training and experience substantial physiological stress, which could affect the composition and function of their gut microbiome. This study compared the gut microbiomes of 148 German junior and senior elite athletes with those of 108 healthy adults to identify taxonomic and functional features associated with elite athletic status. Group comparisons were conducted between healthy adults, senior athletes, and junior athletes, and a matched-subgroup analysis was performed in adults only, controlling for age, sex, body mass index, and dietary pattern. Significant differences in taxonomic composition were observed between athletes and healthy adults. Healthy adults exhibited greater microbial evenness and diversity than junior athletes, whereas senior athletes displayed higher microbial richness. Principal coordinate analysis revealed distinct clustering by athletic status. Linear discriminant analysis effect size identified taxa such as

Indexed as

AthletesBacteriaGastrointestinal MicrobiomeAdolescentAdultFemaleGermanyHumansMaleMetagenomicsYoung Adultathletesenergy metabolismhealthy adultsmatched subgroupstress regulation

Identifiers

PMID42377028
PMCPMC13387018

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.