Evidence map›Paper›PMID 42377135›Full record

ArticleInfection and immunity2026

Emma Lea Matthews, Meghan June Hirsch, Kuen-You Tsai, Hannah J McIntire-Ray, Viviana Acevedo Rua, Angela N Morales, Luke I Jones, Jarrod W Barnes, Megan R Kiedrowski, Stefanie Krick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emma Lea MatthewsDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-7385-7249
Meghan June HirschDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Kuen-You TsaiDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Hannah J McIntire-RayDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Viviana Acevedo RuaDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Angela N MoralesDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Luke I JonesDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jarrod W BarnesDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Megan R KiedrowskiDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-4610-182X
Stefanie KrickDivision of Pulmonary, Allergy & Critical Care Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-8284-6768

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul A. Goepfert · 1988 to 2026
$84.1M
UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMIT GAGGAR · 2007 to 2026
$23.0M
Targeting fibroblast growth factor receptors in cystic fibrosis-associated airway inflammation and mucociliary dysfunctionR01HL160911 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Stefanie Krick · 2022 to 2026
$2.1M
Epigenetic Modulation of Cellular Senescence in the Cystic Fibrosis LungR01HL169253 · NHLBI · OLD DOMINION UNIVERSITY · PI Stefanie Krick, Yan Sanders · 2024 to 2026
$1.9M
Training Program in Cell, Molecular, and Developmental BiologyT32GM146611 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Susan L Bellis · 2024 to 2026
$1.4M
NCI NIH HHS P30 CA013148NHLBI NIH HHS R01 HL160911NHLBI NIH HHS R01HL160911NHLBI NIH HHS R01 HL169253NHLBI NIH HHS R01HL169253NIAID NIH HHS P30 AI027767NIDDK NIH HHS P30 DK072482NIGMS NIH HHS 1T32GM146611NIGMS NIH HHS T32 GM146611
6 · The paper itself

Abstract

Cystic fibrosis (CF) is a genetic disorder that causes chronic airway disease, leading to accelerated aging, inflammation, and susceptibility to opportunistic infections.

Indexed as

BronchiCystic FibrosisLysosomesPseudomonas aeruginosaPseudomonas InfectionsRespiratory Mucosabeta-GalactosidaseCellular SenescenceCytokinesEpithelial CellsHumansSirolimusbeta-GalactosidaseCytokinesSirolimusbronchial epitheliumcellular senescencecystic fibrosislysosomePseudomonas aeruginosapulmonary infection

Identifiers

PMID42377135
PMCPMC13459585

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.