Evidence map›Paper›PMID 42377935›Full record

ReviewFEMS yeast research2026

Yeasts in the gastrointestinal tract.

Katherine D Mueller, Soo Chan Lee

Abstract readReview
In one paragraph

Review in FEMS yeast research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katherine D MuellerDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, United States.
Soo Chan LeeDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, United States.ORCID 0000-0002-7792-5947

Funding

A novel link between calcineurin, amino acid permease, and protein kinase A in virulence in MucorR01AI182221 · NIAID · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI Soo Chan Lee · 2025 to 2026
$1.1M
NIAID NIH HHS R01 AI182221NIAID NIH HHS R01-AI182221NIH
6 · The paper itself

Abstract

The human gastrointestinal (GI) microbiota has come to be recognized as a modulator of health. However, interest in fungi and their function as members of the microbiota has lagged behind interest in bacteria. Despite the lack of historical interest, fungi are prevalent in the human GI tract and have an outsized impact on host immunity. In this review, we aim to examine the associations and potential impact of yeasts on human health outcomes. This review summarizes the associations between yeasts and inflammatory bowel diseases, highlights the predictive service that yeasts may provide in cancer therapy, and explores the possibility of yeasts as therapeutic effectors. There remain significant challenges in data analysis and identifying the relevance of fungal morphology; however, the pathways for clinical translation open to yeasts in the GI tract make these challenges worth overcoming.

Indexed as

Gastrointestinal MicrobiomeGastrointestinal TractYeastsHumansInflammatory Bowel DiseasesProbioticsfungal microbiomefungi in GI tractinflammatory bowel diseasesmycobiomeprobiotics

Identifiers

PMID42377935
PMCPMC13355319

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.