Evidence map›Paper›PMID 42379767›Full record

ArticleIn vivo (Athens, Greece)

Exploring the Contribution of Interleukin-12A Genetic Polymorphisms to Pterygium Risk.

Ya-Chen Yang, Ning-Yi Hsia, Te-Chun Hsia, Pei-Shin Hu, Wen-Shin Chang, Chia-Wen Tsai, DA-Tian Bau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ya-Chen Yang *Department of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan, R.O.C.
Ning-Yi Hsia *Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Te-Chun Hsia *Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Pei-Shin HuDepartment of Ophthalmology, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Wen-Shin ChangTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Chia-Wen TsaiTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.
DA-Tian BauTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan, R.O.C.; 013280@tool.caaumed.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPterygium is a common ocular surface disorder with multifactorial etiology involving environmental exposure and immune dysregulation. Interleukin-12 (IL-12), a key immunomodulatory cytokine, has been implicated in inflammation and tumor-related processes, yet its genetic contribution to pterygium remains unclear. This study aimed to evaluate the association between MATERIALS AND

methodsA hospital-based case-control study was conducted, including 160 pterygium patients and 320 age- and sex-matched controls. Genotyping of

resultsBoth polymorphisms were in Hardy-Weinberg equilibrium among controls (

conclusionDespite the tumor-like and inflammatory characteristics of pterygium,

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseInterleukin-12 Subunit p35Polymorphism, Single NucleotidePterygiumAgedAllelesCase-Control StudiesFemaleGene FrequencyGenotypeHumansMaleMiddle AgedRisk FactorsInterleukin-12 Subunit p35Genotypesinterleukin-12pterygiumsingle nucleotide polymorphismTaiwan

Identifiers

PMID42379767
PMCPMC13321958

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.