Evidence map›Paper›PMID 42380569›Full record

ArticleScientific reports2026

Akkermansia muciniphila supplementation alters inflammatory profiles across diverse models of colitis.

Jensine A Grondin, Huaqing Wang, Sabah Haq, Charissa Cheng, Hooman Derakhshani, Lesley MacNeil, Michael G Surette, Waliul I Khan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jensine A GrondinFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada.
Huaqing WangFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada.
Sabah HaqFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada.
Charissa ChengFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada.
Hooman DerakhshaniFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada.
Lesley MacNeilFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada.
Michael G SuretteFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada.
Waliul I KhanFarncombe Family Digestive Health Research Institute, McMaster University Health Sciences Centre, Hamilton, ON, Canada. khanwal@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation and is thought to result from interactions among the immune system, environmental factors, and the gut microbiota in genetically susceptible individuals. Akkermansia muciniphila, a commensal bacterium has been reported to be depleted in individuals with IBD, although its precise role in intestinal inflammation remains unclear. This study examined the effects of A. muciniphila across multiple models of colitis, including dextran sulphate sodium (DSS)-induced colitis, the Mucin-2 knockout (Muc2

Indexed as

Akkermansia muciniphilaColitisGut microbiotaInflammatory bowel diseaseIntestinal inflammation

Identifiers

PMID42380569
PMCPMC13616739

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.