Evidence map›Paper›PMID 42381068›Full record

Trial reportWorld journal of surgical oncology2026

Impact of reinforced pancreaticojejunostomy with or without tissue adhesive glue modified cyanoacrylate following pancreaticoduodenectomy: a randomized controlled clinical trial.

Saleh Khairy Saleh, Mohamed Sadek Farahat, Tantawi Abdelnaeem Mohamed, Mina Makram Hendy

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06756074 (Impact of Reinforced Pancreaticojejunostomy With or Without Tissue Adhesive Glue Modified Cyanoacrylate), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06756074 phase2recruitingnot on this map

Impact of Reinforced Pancreaticojejunostomy With or Without Tissue Adhesive Glue Modified Cyanoacrylate (Glubran 2) Following Pancreaticoduodenectomy, Randomized Controlled Clinical Trial.

TypeinterventionalSponsorMinia UniversityRan2025 to 2026Enrolled100ConditionsPancreatic Fistula, Pancreas Cancer, Periampullary Carcinoma, Pancreatic Ductal AdenocarcinomaArmsReinforced pancreaticojejunostomy with tissue adhesive glue modified cyanoacrylate (glubran 2), Pancreaticojejunostomy without tissue adhesive glue modified cyanoacrylate (glubran 2)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saleh Khairy SalehDepartment of Surgery, Faculty of Medicine, Minia University, Minia, Egypt. salehkhairy@mu.edu.eg.ORCID https://orcid.org/0000-0002-2234-7561
Mohamed Sadek FarahatDepartment of Surgery, Faculty of Medicine, Minia University, Minia, Egypt.
Tantawi Abdelnaeem MohamedDepartment of Surgery, Faculty of Medicine, Minia University, Minia, Egypt.
Mina Makram HendyDepartment of Surgery, Faculty of Medicine, Minia University, Minia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative pancreatic fistula (POPF) remains the most significant complication following pancreaticoduodenectomy (PD). This randomized controlled trial evaluated the efficacy of reinforcing the pancreaticojejunostomy (PJ) with Glubran

methodsThis single-center randomized controlled trial with blinded patients and blinded outcome assessors enrolled 100 consecutive patients undergoing open PD for pancreatic head or periampullary cancer between 15 January 2025 and 15 January 2026. Patients were randomized 1:1 to Glubran

resultsPOPF (Grade B/C) occurred in 3 patients (6%) in the Glubran

conclusionsIn this single-center randomized trial, reinforcement of pancreaticojejunostomy with Glubran

trial registrationClinicalTrials.gov NCT06756074. Registered 24 December 2024 (prospective). https://clinicaltrials.gov/study/NCT06756074 .

Indexed as

CyanoacrylatesPancreatic FistulaPancreatic NeoplasmsPancreaticoduodenectomyPancreaticojejunostomyPostoperative ComplicationsTissue AdhesivesAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisCyanoacrylatesglubran 2Tissue AdhesivesCyanoacrylateGlubran®2PancreaticoduodenectomyPancreaticojejunostomyPostoperative pancreatic fistulaRandomized controlled trialTissue adhesive

Identifiers

PMID42381068
PMCPMC13317045

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.