Evidence map›Paper›PMID 42383013›Full record

ArticleiScience2026

Bioactive carbon dots from peony seed meal for nanomedicine via circular economy.

Zhi-Fang Liu, Qi Wang, Jian-Hua Xiao, Jiang-Hui Wang, Jian Li, Chen-Jing Han, Seid Mahdi Jafari, Zhi-Yuan Lu

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhi-Fang LiuInstitute of Leisure Agriculture, Shandong Academy of Agricultural Sciences, Jinan, China.
Qi WangInstitute of Leisure Agriculture, Shandong Academy of Agricultural Sciences, Jinan, China.
Jian-Hua XiaoGuangdong Provincial Key Laboratory of Conservation and Precision Utilization of Characteristic Agricultural Resources in Mountainous Areas, Jiaying University, Meizhou, China.
Jiang-Hui WangInstitute of Leisure Agriculture, Shandong Academy of Agricultural Sciences, Jinan, China.
Jian LiInstitute of Leisure Agriculture, Shandong Academy of Agricultural Sciences, Jinan, China.
Chen-Jing HanInstitute of Leisure Agriculture, Shandong Academy of Agricultural Sciences, Jinan, China.
Seid Mahdi JafariInstitute of Leisure Agriculture, Shandong Academy of Agricultural Sciences, Jinan, China.
Zhi-Yuan LuSchool of Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The valorization of agricultural waste into high-value nanomaterials is key to a sustainable circular economy. Here, we transform underutilized peony seed meal into nitrogen/oxygen-doped carbon dots (PSM-CDs) via a simple hydrothermal process. These PSM-CDs exhibit potent superoxide dismutase-mimetic activity, governed by surface carbonyl groups. In a hemolytic anemia model, they act as a dual-pathway therapeutic by scavenging reactive oxygen species and suppressing the NF-κB/NLRP3 axis, while promoting erythropoiesis via ROS-HIF-1 signaling, with excellent biosafety. This work establishes a scalable "waste-to-therapeutics" paradigm, bridging sustainable agriculture and nanomedicine development.

Indexed as

applied sciencesbiological waste treatmentbiosafetynanomaterials

Identifiers

PMID42383013
PMCPMC13315766

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.