Evidence map›Paper›PMID 42383104›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2026

The United States Leads the Globe in Venture Capital Funding for Orthopaedic Surgery.

Mathangi Sridharan, Charlotte F Wahle, Paul Walker, Luke Barry, Jonathan Yu, Frank Petrigliano, Lauren Wessel, Andrew R Jensen

Abstract read
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In one paragraph

Article in Arthroscopy, sports medicine, and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mathangi SridharanDepartment of Orthopaedic Surgery University of California, Los Angeles Santa Monica California U.S.A.ORCID https://orcid.org/0009-0007-8134-4428
Charlotte F WahleDavid Geffen School of Medicine University of California, Los Angeles Los Angeles California U.S.A.
Paul WalkerDepartment of Orthopaedic Surgery University of California, Los Angeles Santa Monica California U.S.A.ORCID https://orcid.org/0009-0006-0263-5765
Luke BarryDepartment of Epidemiology Fielding School of Public Health University of California, Los Angeles Los Angeles California U.S.A.ORCID https://orcid.org/0000-0001-7772-4822
Jonathan YuDepartment of Orthopaedic Surgery University of California, Los Angeles Santa Monica California U.S.A.ORCID https://orcid.org/0000-0002-6097-956X
Frank PetriglianoDepartment of Orthopaedic Surgery University of California, Los Angeles Santa Monica California U.S.A.
Lauren WesselDepartment of Orthopaedic Surgery University of California, Los Angeles Santa Monica California U.S.A.ORCID https://orcid.org/0000-0002-6240-5981
Andrew R JensenDepartment of Orthopaedic Surgery University of California, Los Angeles Santa Monica California U.S.A.

Funding

Biomedical Data Science Training Program for Precision Health EquityT15LM013976 · NLM · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEX BUI · 2022 to 2026
$1.9M
NLM NIH HHS T15 LM013976
6 · The paper itself

Abstract

Purpose: To characterize venture capital (VC) investments in orthopaedic surgery over the past 25 years to evaluate trends in global innovation. Methods: All VC investments related to orthopaedic surgery between January 2000 and December 2024 were retrospectively evaluated using the PitchBook database (PitchBook Platform, PitchBook Data. Seattle, WA). The headquarter location of each company was reviewed. The year of each investment deal and investment size (US dollars) were aggregated. Deals were also evaluated with respect to funding category (surgical devices, biotechnology, drug discovery, hospital management/technology, medical equipment). Descriptive statistics, compound annual growth rate, 2-sample Results: A total of $9.7 billion (in 2025 USD) in VC funding was invested in orthopaedic surgery, consisting of 1506 distinct deals. VC funding has steadily increased since 2000, most notably between 2020 and 2024, with 49.8% (750) of deals ( Conclusions: VC funding in orthopaedic surgery has steadily increased over the past 25 years, largely concentrated in the United States, with a dramatic increase in the past 5 years driven by interest in orthobiologic therapies and digital health. Clinical Relevance: VC investment trends in orthopaedic surgery appear to mirror many of the broader macroeconomic forces seen in the health care sector and have a direct impact on future development, innovation, and clinical practice within orthopaedic surgery.

Identifiers

PMID42383104
PMCPMC13307463

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.