Evidence map›Paper›PMID 42383197›Full record

ArticleBioactive materials2026

Janus electrospun nanofiber membranes from bio-based furan polyamides for antibacterial wound care.

Xiang Ding, Naing Tun Thet, Carmelo Herdes, Edward Chaloner, Mikal Negasi, Ioanna Kontou, Maisem Laabei, Ute Jungwirth, Dominic Savage, Muhammad Kamran and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiang DingDepartment of Chemistry, University of Bath, Bath, BA2 7AY, UK.
Naing Tun ThetDepartment of Chemistry, University of Bath, Bath, BA2 7AY, UK.
Carmelo HerdesDepartment of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK.
Edward ChalonerDepartment of Life Sciences, University of Bath, Bath, BA2 7AY, UK.
Mikal NegasiNewcastle Drug Discovery Group, Translational and Clinical Research Institute, Newcastle University, Newcastle, NE2 4HH, UK.
Ioanna KontouDepartment of Life Sciences, University of Bath, Bath, BA2 7AY, UK.
Maisem LaabeiSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Ute JungwirthDepartment of Life Sciences, University of Bath, Bath, BA2 7AY, UK.
Dominic SavageDepartment of Chemistry, University of Bath, Bath, BA2 7AY, UK.
Muhammad KamranDepartment of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK.
Michael ZachariadisImaging Facility, Core Research Facilities, University of Bath, Bath, BA2 7AY, UK.
Toby JenkinsDepartment of Chemistry, University of Bath, Bath, BA2 7AY, UK.
Matthew G DavidsonDepartment of Chemistry, University of Bath, Bath, BA2 7AY, UK.
Hannah S LeeseDepartment of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early-stage bacterial contamination and rapid biofilm growth are critical barriers to effective wound healing, highlighting the need for dressing materials that enable prompt, localised antibacterial intervention while maintaining cytocompatibility and sustainability. Here, we report a sustainable electrospun Janus nanofiber membrane based on two bio-derived semi-aromatic furan polyamides, poly(octamethylene furanamide) (PA8F) and poly(decamethylene furanamide) (PA10F), for antibacterial wound dressing applications. Although PA8F and PA10F differ only by two methylene units and show modest wettability differences as dense films, electrospinning into nanofiber networks amplifies this subtle molecular contrast into a pronounced, robust wettability asymmetry that enables a Janus dressing architecture without chemical surface modification. Tetracycline was physically dispersed within the hydrophilic PA8F, prior to electrospinning, to localise antibiotic delivery at the wound-material interface. The Janus membrane exhibits uniform, bead-free nanofibrous morphology and pronounced interfacial wettability asymmetry. Molecular dynamics simulations reveal distinct polymer-water interaction behaviours that underpin the experimentally observed hydration contrast between PA8F and PA10F. Drug release studies demonstrate rapid antibiotic availability, reaching ∼20 μg mL

Indexed as

AntibacterialElectrospinningJanus membraneSustainableWound dressing

Identifiers

PMID42383197
PMCPMC13316687

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.