Evidence map›Paper›PMID 42384639›Full record

Trial reportSexual and reproductive health matters2025

Evaluating the effects of a multi-level intervention on young women's contraceptive use: sexual and reproductive health results of a cluster-randomised factorial-design study in Tshwane, South Africa.

Ilene S Speizer, Courtney P Bonner, Laura Nyblade, Jacqueline Ndirangu, Alexandra Minnis, Khatija Ahmed, Tracy L Kline, Felicia A Browne, Brittni Howard, Wendee M Wechsberg

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Sexual and reproductive health matters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilene S SpeizerProfessor, Department of Maternal and Child Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Faculty Fellow Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Correspondence: ilene_speizer@unc.edu.ORCID 0000-0001-6204-1316
Courtney P BonnerSenior Research Psychologist, RTI International, Durham, NC, USA.ORCID 0000-0001-6983-2698
Laura NybladeFellow and Senior Technical Advisor, RTI International, Durham, NC, USA.ORCID 0000-0001-8067-4192
Jacqueline NdiranguSenior Public Health Analyst, RTI International, Durham, NC, USA.
Alexandra MinnisPublic Health Director, RTI International, Durham, NC, USA.ORCID 0000-0002-2943-2005
Khatija AhmedInvestigator, Setshaba Research Centre, Tshwane City, South Africa; Researcher, Department of Paediatrics & Child Health, in the School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-0309-1641
Tracy L KlineSenior Manager Research Psychometrician, RTI International, Durham, NC, USA.ORCID 0000-0002-6675-0360
Felicia A BrowneSenior Research Social Epidemiologist, RTI International, Durham, NC, USA.ORCID 0000-0002-4230-2096
Brittni HowardPublic Health Analyst III, RTI International, Durham, NC, USA.
Wendee M WechsbergAdjunct Professor, Department of Maternal and Child Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Principal Investigator Emerita, RTI International, Durham, NC, USA.ORCID 0000-0002-5146-6463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In South Africa, adolescent girls and young women (AGYW) are engaged in early, condomless, and unprotected (from pregnancy) sex, which puts them at risk of unintended pregnancies and sexually transmitted infections. At the individual, interpersonal, and structural levels, AGYW experience barriers to their access to and use of contraception and condoms. This study employed a cluster-randomised factorial design to examine the impact of a multi-level intervention on contraceptive use behaviours among 802 women ages 16-24 in Tshwane, South Africa. The two intervention components were the Young Women's Health CoOp (YWHC), an intervention to increase participants' knowledge and skills, and a stigma and discrimination (S&D) reduction training at the facility level. Study facilities were randomised into the four study arms: YWHC only; S&D only; both YWHC and S&D; and control (standard of care). The study demonstrated that AGYW in the YWHC arm (RRR: 2.45; 95% CI: 1.05-5.70,

Indexed as

Contraception BehaviorHealth Knowledge, Attitudes, PracticeAdolescentCondomsContraceptionFemaleHumansPregnancyReproductive HealthSexual BehaviorSexual HealthSouth AfricaYoung Adultadolescent girls and young womencontraceptive useevaluationinterventionSouth Africastigma and discrimination

Identifiers

PMID42384639
PMCPMC13431016

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.