Evidence map›Paper›PMID 42384640›Full record

ArticlePloS one2026

An exercise-associated gut microbiota signature enhances endurance performance: A study combining a human cohort and a mice FMT model.

Xiongbao Zhang, Yating Fu, Jiahui Chen, Hao Shen, Yumeng Du, Jun Wu, Hongjing Lai, Yu Liu, Jingbo Chen, Xiaomei Hou and 2 more

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In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Xiongbao ZhangFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Yating FuFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Jiahui ChenFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Hao ShenFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Yumeng DuFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Jun WuSchool of Public Health, China Medical University, Shenyang, China.
Hongjing LaiSchool of Public Health, China Medical University, Shenyang, China.
Yu LiuFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Jingbo ChenFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Xiaomei HouDepartment of Internal Medicine, Hospital of Naval Marine Corps, Chaozhou, China.
Wenjun ChangFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Xuefei HuFaculty of Naval Medicine, Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-1840-7787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe gut microbiota is closely related to exercise, but the interrelationship between the two remains elusive. In this study, we aimed to explore differences in the gut microbiota between young adults with exercise and sedentary lifestyles. In addition, we evaluated the effects of gut microbiota from these different lifestyle populations on endurance exercise capacity.

methodsThe exercise status and nutritional characteristics of young adults were evaluated by PARS-3 and food frequency questionnaires. The gut microbiota of young adults from exercise and sedentary lifestyle groups was analyzed by 16S rRNA analysis. Subsequently, we performed fecal bacteria transplantation (FMT) from the human donors into mice and evaluated the effects on their endurance exercise capacity.

resultsThe exercise group exhibited significantly higher gut microbiota diversity compared to the sedentary group. Several beneficial bacteria, including Veillonella, Faecalibacterium, and Bacteroides, were enriched in the exercise group. The FMT experiment confirmed that mice receiving microbiota from the exercise group showed significantly improved endurance exercise capacity.

conclusionYoung people who exercise regularly possess a more diverse gut microbiota enriched with beneficial bacteria. This exercise-associated microbiota has the potential to directly improve exercise capacity.

Indexed as

ExerciseFecal Microbiota TransplantationGastrointestinal MicrobiomePhysical EnduranceAdultAnimalsCohort StudiesFecesFemaleHumansMaleMiceRNA, Ribosomal, 16SYoung AdultRNA, Ribosomal, 16S

Identifiers

PMID42384640
PMCPMC13322530

What Socratic holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.