Evidence map›Paper›PMID 42384758›Full record

ArticleEpigenetics2026

Dnmt1 associated

Yang Liu, Zijun Wang, Youxiao Zhao, Yanyan Ma, Jing Yi, Yingnan Song, Yanqiu Liu, Li An, Zhijun Pan, Hong Gao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yang LiuDepartment of Anesthesiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.ORCID 0000-0001-8049-3498
Zijun WangDepartment of Anesthesiology, The Affiliated Jinyang Hospital of Guizhou Medical University, The Second People's Hospital of Guiyang, Guiyang, Guizhou, China.ORCID 0000-0002-0532-8940
Youxiao ZhaoSchool of Anesthesiology, Guizhou Medical University, Guiyang, Guizhou, China.
Yanyan MaDepartment of Anesthesiology, The First People's Hospital of Zunyi, Zunyi, Guizhou, China.ORCID 0000-0001-5780-1173
Jing YiDepartment of Anesthesiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Yingnan SongGuizhou Medical University Key Laboratory of Cardiovascular Disease Basic and Clinical Research, Department of Physiology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, Guizhou, China.
Yanqiu LiuDepartment of Anesthesiology, The Fourth People's Hospital of Guiyang, Guiyang, Guizhou, China.
Li AnDepartment of Anesthesiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Zhijun PanDepartment of Anesthesiology, Guiyang Maternal and Child Health Care Hospital and Guiyang Children's Hospital, Guiyang, Guizhou, China.
Hong GaoDepartment of Anesthesiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.ORCID 0000-0002-3555-5570
Ying CaoDepartment of Anesthesiology, The Affiliated Jinyang Hospital of Guizhou Medical University, The Second People's Hospital of Guiyang, Guiyang, Guizhou, China.ORCID 0000-0003-0699-1039

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation has traditionally been regarded as a stable epigenetic modification. However, emerging evidence indicates that oxidative and genotoxic stress can induce locus-specific methylation changes that modulate transcriptional responses. The contribution of such dynamic regulation to cardiac gene expression during myocardial ischemia/reperfusion injury (MIRI) remains incompletely understood. This study investigated whether altered methylation changes within the

Indexed as

Connexin 43DNA (Cytosine-5-)-Methyltransferase 1DNA MethylationMyocardial Reperfusion InjuryPromoter Regions, GeneticAnimalsAzacitidineEpigenesis, GeneticMaleMiceMice, Inbred C57BLAzacitidineConnexin 43DNA (Cytosine-5-)-Methyltransferase 1Dnmt1 protein, mouseGJA1 protein, mouseconnexin 43 remodelingDNA methylationDnmt1epigenetic regulationMIRImyocardial ischemia/reperfusion injury

Identifiers

PMID42384758
PMCPMC13336278

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.