Evidence map›Paper›PMID 42385747›Full record

ArticleHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme2026

Determinants of Infant Participation and Non-Participation in Primary Prevention Trials.

Franziska Wörl, Peter Achenbach, Ezio Bonifacio, Kristina Casteels, Gita Gemulla, Florian Haupt, Sophia Hawkins, Angela Hommel, Sharon King, Olga Kordonouri and 17 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Franziska WörlLudwig-Maximilians-Universität München, Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Chair of Public Health and Health Service Research, LMU Medizin, Germany, Munich.
Peter AchenbachHelmholtz Munich, German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Ezio BonifacioTechnische Universität Dresden, Center for Regenerative Therapies Dresden, Germany, Dresden.
Kristina CasteelsKU Leuven, Department of Development and Regeneration, Flanders, Belgium, Leuven.
Gita GemullaUniversity Hospital Carl Gustav Carus, Technische Universität Dresden, Department of Pediatrics, Germany, Dresden.
Florian HauptHelmholtz Munich, German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Sophia HawkinsUniversity of Oxford, Oxford Vaccine Group, Department of Paediatrics, England, United Kingdom of Great Britain and Northern Ireland, Oxford.
Angela HommelTechnische Universität Dresden, Center for Regenerative Therapies Dresden, Germany, Dresden.
Sharon KingThe Great North Children's Hospital, Royal Victoria Infirmary, Newcastle upon Tyne, General Paediatrics, UK.
Olga KordonouriAUF DER BULT, Kinder- und Jugendkrankenhaus, Germany, Hanover.
Helena Elding LarssonLund University, Unit for Pediatric Endocrinology, Department of Clinical Sciences Malmö, Skåne County, Sweden, Lund.
Anja LoffTechnische Universität Dresden, Center for Regenerative Therapies Dresden, Germany, Dresden.
Markus LundgrenLund University, Unit for Pediatric Endocrinology, Department of Clinical Sciences Malmö, Skåne County, Sweden, Lund.
Hannah NenonenLund University, Unit for Pediatric Endocrinology, Department of Clinical Sciences Malmö, Skåne County, Sweden, Lund.
Mariusz OłtarzewskiInstitute of Mother and Child, Department of Screening and Metabolic Diagnostics, Poland, Warsaw.
Catherine OwenThe Great North Children's Hospital, Royal Victoria Infirmary, Newcastle upon Tyne, General Paediatrics, UK.
Jasmin PaulusUniversity Hospital Gasthuisberg, Research & Development Endocrinology, Belgium, Leuven.
Stephen RobsonThe Great North Children's Hospital, Royal Victoria Infirmary, Newcastle upon Tyne, General Paediatrics, UK.
Frank RoloffAUF DER BULT, Kinder- und Jugendkrankenhaus, Germany, Hanover.
Matthew SnapeOxford Vaccine Group, University of Oxford Department of Paediatrics, and NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, , UK.
Agnieszka SzypowskaInstitute of Mother and Child, Department of Screening and Metabolic Diagnostics, Poland, Warsaw.
Manu VatishNuffield Department of Women's & Reproductive Health, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Andreas WeißHelmholtz Munich, German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Christiane WinklerHelmholtz Munich, German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Anna ZychDepartment of Paediatric Diabetology and Paediatrics, The Children's Clinical Hospital Józef Polikarp Brudziński, University Clinical Centre of the Medical University of Warsaw, Warsaw, Poland.
Anette-G ZieglerHelmholtz Munich, German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Sandra HummelHelmholtz Munich, German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.ORCID 0000-0001-6554-5974

Funding

Bundesministerium für Bildung und Forschung FKZ: 01KX1818EASD-Novo Nordisk Foundation Diabetes Prize for Excellence to AGZ (Helmholtz Munich) NNF22SA0081044The Leona M. and Harry B. Helmsley Charitable Trust #2018PG-T1D022 and #2003-04286The Leona M. and Harry B. Helmsley Charitable Trust #2018PG-T1D023 and #2007-04031
6 · The paper itself

Abstract

Abstract: Understanding the determinants that influence parents' decisions to participate with their infants in primary prevention trials is essential for achieving representative study samples and ensuring the generalizability of outcomes. We analyzed quantitative and qualitative data collected from infants eligible for the Primary Oral Insulin Trial (

Indexed as

Diabetes Mellitus, Type 1Patient ParticipationPrimary PreventionFemaleHumansInfantInfant, NewbornInsulinMaleRandomized Controlled Trials as TopicInsulin

Identifiers

PMID42385747
PMCPMC13456943

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.