Evidence map›Paper›PMID 42386744›Full record

ArticleNature communications2026

Interferon-elicited lipoprotein metabolism in lung fibroblasts facilitates premetastatic niche formation.

Jian Gao, Yilan Huang, Xiaojun Zhang, Chao Gao, Yiran Zhuang, Zheng Han, Mingyu Xia, Chun Jin, Dingguo Wang, Lingxian Zhang and 5 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jian Gao *Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-6400-7290
Yilan Huang *Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiaojun Zhang *Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Chao Gao *Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Yiran ZhuangSecond Military Medical University (Naval Medical University), Shanghai, China.
Zheng HanDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Mingyu XiaDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Chun JinDepartment of Thoracic Surgery, Changhai Hospital, Second Military Medical University (Naval Medical University), Shanghai, China.
Dingguo WangDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Lingxian ZhangDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jiazhe WenDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Lefan JinSchool of Public Health and the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Yongqiang AoDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. 23111210077@m.fudan.edu.cn.ORCID http://orcid.org/0000-0002-0334-0161
Jiahao JiangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. jiang.jiahao@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0002-9164-8843
Jianyong DingDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. ding.jianyong@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0003-2729-3141

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82403999National Natural Science Foundation of China (National Science Foundation of China) 82472924
6 · The paper itself

Abstract

While premetastatic niche formation is known to affect primary tumors lung metastases, the role of lung stromal cells in this process remains unclear. Here, by performing multiomics sequencing, we identify interferon-regulated CD34

Indexed as

FibroblastsInterferonsLipoproteinsLungLung NeoplasmsAnimalsCell Line, TumorFemaleHumansKiller Cells, NaturalMetabolic ReprogrammingMiceMice, Inbred C57BLReceptors, LDLSTAT1 Transcription FactorT-Lymphocytes, CytotoxicInterferonsLipoproteinsReceptors, LDLSTAT1 Transcription Factor

Identifiers

PMID42386744
PMCPMC13462697

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.