SynthesisNature human behaviour2026
Interoception in self-harm and suicide: a scoping review and meta-analysis.
Synthesis in Nature human behaviour, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Relationship Between Heart Rate Variability and Interoception in Anorexia Nervosa Spectrum Disorders.The International journal of eating disorders · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Interoception, the capacity to sense and interpret internal bodily signals, has been recognized as relevant to self-harm and suicide, but these associations and their dimensional specificity have not been quantitatively synthesized. This scoping review and meta-analysis aimed to estimate the magnitude of associations between interoceptive dimensions and self-harm (that is, non-suicidal self-injury and self-harm (mixed intent)) and suicidal outcomes (ideation, plans and attempts), and to explore the neural mechanisms implicated in these associations. We searched PubMed, Web of Science, PsycINFO and EMBASE from inception to 1 April 2025. Sixty-six studies (36,934 participants) were included, comprising 63 observational studies (59 cross-sectional and 4 longitudinal/prospective) and 3 intervention studies, of which 41 contributed a study to the meta-analysis. Interoception was classified into four previously validated dimensions: accuracy, sensibility, awareness and 'Other' (or cognitive-emotional evaluation of bodily signals). Interoceptive accuracy demonstrated weak and non-significant associations with self-harm and suicidal outcomes. Interoceptive sensibility showed generally negative associations across outcomes, with increased trust in bodily signals and self-regulation (that is, ability to regulate distress via attention to bodily sensations) associated with lower levels of suicidal ideation, suicide attempts and composite suicidal outcomes, with generally small-to-moderate effect sizes. Interoceptive awareness was not meta-analysed owing to insufficient evidence. Within the 'Other' (or cognitive-emotional evaluation) dimension, interoceptive deficits were positively associated with non-suicidal self-injury and suicidal ideation. Neuroimaging studies implicated altered interoceptive processing in the insula and prefrontal cortex, suggesting shared neural substrates of interoceptive abnormalities and suicide risk, although the evidence remains preliminary. These findings highlight interoception as a potentially informative domain for advancing the understanding of risk processes underlying self-harm and suicidality, and for informing future research on how bodily awareness and regulation relate to self-harm and suicidal risk.
Indexed as
Identifiers
42386917What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.