ArticleNature cancer2026
IDH1-mutant vaccine in newly diagnosed astrocytoma: final analysis of the multicenter, single-arm, open-label, first-in-human phase 1 NOA16 trial.
Erratum issuedAbstract readMulticenter StudyClinical Trial, Phase I
In one paragraph
Article in Nature cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Immunotherapy for Newly Diagnosed Glioblastoma: Current Evidence and Future Perspectives.Journal of personalized medicine · 2026Review
- IDH-Mutant Diffuse Glioma: From Metabolic Origins to Targeted Therapy.Journal of clinical medicine · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
27 authors.
Lukas BunseDKTK (German Cancer Consortium) Clinical Cooperation Unit (CCU) Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany. l.bunse@dkfz.de.ORCID http://orcid.org/0000-0002-4490-7574
Katharina LindnerDKTK (German Cancer Consortium) Clinical Cooperation Unit (CCU) Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-2735-3266
Antje WickNeurology Clinic and European Center for Neurooncology (EZN), Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.
Angelika FreitagNCT Trial Management and Services, NCT, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Lisa-Marie LanzNCT Trial Management and Services, NCT, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Dominic EdelmannNCT Trial Management and Services, NCT, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Abigail SuwalaDepartment of Neuropathology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.
Michael O BreckwoldtDepartment of Neuroradiology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.
Inga HartingDepartment of Neuroradiology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.
Felix SahmDepartment of Neuropathology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-5441-1962
Richard F SchlenkGerman Cancer Consortium (DKTK), DKFZ, Core Center, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-2215-2059
Anita SchmittDepartment of Internal Medicine V, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.
Oliver SchnellNeurosurgery Clinic, University Hospital Erlangen, Erlangen, Germany.
Jörg HenseDepartment of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Martin MischDepartment of Neurosurgery, Charité Medical Center, University of Berlin, Berlin, Germany.
Dietmar KrexTechnische Universität Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, Department of Neurosurgery, Dresden, Germany.
Monika DenkCluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.
Juliane WalzCluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0001-6404-7391
Joachim P SteinbachDr. Senckenberg Institute of Neurooncology, Frankfurt, Germany.
Andreas von DeimlingDepartment of Neuropathology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-5863-540X
Michael SchmittDepartment of Internal Medicine V, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-1579-1509
Theresa BunseDKTK (German Cancer Consortium) Clinical Cooperation Unit (CCU) Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0003-1834-4269
Ghazaleh TabatabaiCluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-3542-8782
Martin BendszusDepartment of Neuroradiology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.
Isabel PoschkeDKTK (German Cancer Consortium) Clinical Cooperation Unit (CCU) Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Wolfgang WickGerman Cancer Consortium (DKTK), DKFZ, Core Center, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6171-634X
Michael PlattenDKTK (German Cancer Consortium) Clinical Cooperation Unit (CCU) Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.platten@dkfz.de.ORCID http://orcid.org/0000-0002-4746-887X
Funding
Deutsche Forschungsgemeinschaft (German Research Foundation) SFB1389
Abstract
The clonal glioma driver mutation IDH1
Indexed as
AstrocytomaBrain NeoplasmsCancer VaccinesIsocitrate DehydrogenaseMutationAdultAgedFemaleHumansMaleMiddle AgedProtein Subunit VaccinesVaccines, SubunitCancer VaccinesIDH1 protein, humanIsocitrate DehydrogenaseProtein Subunit VaccinesVaccines, Subunit
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.