Evidence map›Paper›PMID 42387408›Full record

ArticleBMC geriatrics2026

Risk factors of postoperative non-compliance behavior in elderly patients with gastrointestinal malignant tumors.

Baoli Tang, Hao Zheng, Huagang Wang, Wenhui Xu, Ling Chen, Zilong Zhang

Abstract read
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Baoli TangDepartment of Gastrointestinal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
Hao ZhengDepartment of Gastrointestinal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
Huagang WangDepartment of Gastroenterology, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
Wenhui XuDepartment of Gastrointestinal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
Ling ChenDepartment of Gastrointestinal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
Zilong ZhangDepartment of Gastrointestinal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China. jzszxyyzzl@126.com.ORCID http://orcid.org/0009-0002-5208-6611

Funding

Beijing Bethune Elite Scientific Research Development Fund Project 2023-YJ-041-J-011Wu Jieping Medical Foundation Clinical Research Special Fund Project 320.6750.2024-6-134
6 · The paper itself

Abstract

backgroundElderly patients with gastrointestinal malignancies frequently exhibit postoperative non-compliance behaviors, which includes failure to persist with adjuvant therapy, attend regular follow-up appointments, and take medications strictly as prescribed. These non-compliant behaviors seriously affect the prognosis of patients.

methodsWe conducted a large-scale retrospective study in China, which enrolled 284 elderly patients who underwent surgery for gastrointestinal malignancies at Jingzhou Hospital Affiliated to Yangtze University between February 2018 and February 2023. The patients were randomly divided into a training group (198 patients, 70%) and a validation group (86 patients, 30%). Univariate and multivariate logistic regression analyses were performed to identify independent risk factors for postoperative non-compliance behaviors (P < 0.05), based on which a predictive nomogram was constructed. The model's performance was evaluated using receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis (DCA). Furthermore, all patients were followed up for 2 years, and survival curves were plotted.

resultsThe results showed that education level, disease type, history of heart disease, tumor differentiation, net family income, and living alone were independent risk factors for postoperative non-compliance behaviors in elderly patients with gastrointestinal malignancies (P < 0.05). These factors were incorporated into the construction of a nomogram prediction model. The areas under the curve (AUC) for the training and validation groups were 0.865 (95% CI: 0.814-0.915) and 0.871 (95% CI: 0.797-0.946), respectively. Calibration curve results indicated that the predicted probabilities of the model were in close agreement with the actual observed frequencies in both the training and validation groups, with mean absolute errors of 0.037 and 0.023, respectively. DCA demonstrated that the model provided significant net clinical benefit within threshold probability ranges of 0.11-0.99 for the training group and 0.41-0.91 for the validation group. Kaplan-Meier analysis showed significantly better survival in the compliance group. Disease-free survival (DFS) rates at 6, 12, and 24 months were 90.1%, 85.9%, and 79.6% versus 73.2%, 66.9%, and 62.0% in the non-adherence group (all P < 0.05). Overall survival (OS) was also significantly higher (P < 0.001), with a hazard ratio of 0.28.

conclusionOur research suggests that early intervention for elderly patients with low education levels, lesions located in the colon, comorbid heart disease, low tumor differentiation, low monthly family net income, and living alone who do not follow medical advice after gastrointestinal malignant tumor surgery can change the patient's prognosis.

Indexed as

Gastrointestinal NeoplasmsPatient ComplianceAgedAged, 80 and overChinaFemaleHumansMaleRetrospective StudiesRisk FactorsElderly patientsGastrointestinal malignanciesNomogramPostoperative non-complianceRisk factors

Identifiers

PMID42387408
PMCPMC13599227

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.