Evidence map›Paper›PMID 42388232›Full record

ArticleBiochemistry and biophysics reports2026

Salidroside and mesenchymal stem cells alleviate hypobaric hypoxia-induced lung injury and are associated with alterations in the gut-lung axis.

Dengqin Ma, Bang Xin, Meng Li, Bingfang Xie, Qun Li, Enpen Zhu, Jing Luo, Xiaoqin Ha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dengqin MaThe 940th Hospital of Joint Logistics Support Force of PLA, Lanzhou, 730050, China.
Bang XinSchool of Basic Medical Sciences, Gansu University of Chinese Medicine, Lanzhou, 730000, China.
Meng LiThe 940th Hospital of Joint Logistics Support Force of PLA, Lanzhou, 730050, China.
Bingfang XieThe First People's Hospital of Tianshui, Tianshui, Gansu, 741000, China.
Qun LiThe First People's Hospital of Tianshui, Tianshui, Gansu, 741000, China.
Enpen ZhuThe 940th Hospital of Joint Logistics Support Force of PLA, Lanzhou, 730050, China.
Jing LuoThe 940th Hospital of Joint Logistics Support Force of PLA, Lanzhou, 730050, China.
Xiaoqin HaThe 940th Hospital of Joint Logistics Support Force of PLA, Lanzhou, 730050, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-altitude pulmonary injury (HAPI) results from hypobaric hypoxia and is characterized by excessive inflammation, oxidative imbalance, and disrupted barrier integrity. Salidroside and mesenchymal stem cells (MSCs) have shown protective effects against HAPI. However, it remains unclear whether these effects are associated with alterations in the gut-lung axis and whether combined therapy provides synergistic advantages. A rat model of hypobaric hypoxia was established. Lung injury was assessed by histopathology analysis and determination of IL-6, TNF-α, glutathione (GSH), and catalase (CAT) levels in lung tissues. Gut microbial composition was characterized using

Indexed as

Gut-lung axisGut microbiotaHypobaric hypoxiaLung injuryMesenchymal stem cellsMetabolomicsSalidroside

Identifiers

PMID42388232
PMCPMC13318544

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.