Evidence map›Paper›PMID 42388293›Full record

ReviewFrontiers in digital health2026

Selecting medical research data platforms for translational biomedical research: a five-tier overview and requirement-weighted assessment framework.

Marc Jacobs, Samad Goudarzi, Jan Stücke, Robin Röhm, Timo Kanninen, Tero Oinonen, Petra Ritter, Michael Schirner, Fabian Prasser, Arman Bhagwagar and 21 more

Abstract readReview
In one paragraph

Review in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Marc JacobsBioinformatics Department, Fraunhofer-Institute for Algorithms and Scientific Computing (SCAI), Sankt Augustin, Germany.
Samad GoudarziBioinformatics Department, Fraunhofer-Institute for Algorithms and Scientific Computing (SCAI), Sankt Augustin, Germany.
Jan StückeApheris AI GmbH, Berlin, Germany.
Robin RöhmApheris AI GmbH, Berlin, Germany.
Timo KanninenBC Platforms, Espoo, Finland.
Tero OinonenBC Platforms, Espoo, Finland.
Petra RitterBerlin Institute of Health at Charité - Universitätsmedizin Berlin, Charité, Berlin, Germany.
Michael SchirnerBerlin Institute of Health at Charité - Universitätsmedizin Berlin, Charité, Berlin, Germany.
Fabian PrasserCenter of Health Data Sciences, BIH @ Charité, Berlin, Germany.
Arman BhagwagarDNANexus, Mountain View, CA, United States.
Bernd MatzenbachDNANexus, Mountain View, CA, United States.
Hartmut SchultzeDeutsches Zentrum für Neurodegenerative Erkrankungen, Bonn, Germany.
Joachim SchultzeDeutsches Zentrum für Neurodegenerative Erkrankungen, Bonn, Germany.
Mathias GöschlHiGHmed e.V., Heidelberg, Germany.
Henrik MatthiesHONIC Health Data Technologies GmbH, Neckarsulm, Germany.
Kenneth R EvansIndoc Systems, Toronto, ON, Canada.
Moyez DharseeIndoc Systems, Toronto, ON, Canada.
Christian StephanIQVIA, Bochum, Germany.
Marvin BelzIQVIA, Bochum, Germany.
Philip GribbonFraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Hamburg, Germany.
Katja HerzogFraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Hamburg, Germany.
Chester ChenNVIDIA, Santa Clara, CA, United States.
David RuauNVIDIA, Santa Clara, CA, United States.
Ittai DayanRHINO Federated Computing, Boston, MA, United States.
Adrish SannyasiRHINO Federated Computing, Boston, MA, United States.
Dieter KranzlmüllerLeibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences and Humanities, Garching, Germany.
Naweiluo ZhouLeibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences and Humanities, Garching, Germany.
Jens WarfsmannDivision of Personalized Tumor Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Regensburg, Germany.
Martin HoffmannDivision of Personalized Tumor Therapy, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Regensburg, Germany.
Rudi SchmidtBonn-Aachen International Center for Information Technology (B-IT), University of Bonn, Bonn, Germany.
Martin Hofmann-ApitiusBioinformatics Department, Fraunhofer-Institute for Algorithms and Scientific Computing (SCAI), Sankt Augustin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Translational biomedical research is increasingly collaborative and multimodal, making secure, high-quality data capture, curation, and analytics a major challenge. This work aims to provide an overview of existing medical research data platforms to support informed platform selection for translational biomedical research. Methods: As part of an ongoing Fraunhofer Request for Proposal (RFP) process, we developed a requirements assessment tool for users across the Fraunhofer ecosystem. In parallel, we compiled a structured overview of medical research data platforms through an open collaboration between academic and industry experts, who supplemented our market screening by identifying additional relevant platforms. Using a standardized questionnaire on key aspects of distributed data collaboration, we collected harmonized platform descriptions and organized them into a side-by-side overview with an accompanying feature weighting matrix. Results: The study yielded a structured, comparative characterization of medical research data platforms across five functional classes, highlighting common strengths in security, interoperability, data quality, and multimodal data support. We devised (developed) a platform feature-partner weight matrix that enables context-sensitive platform scoring without imposing a predefined global ranking. In this way, users can align platform scoring with their specific translational research requirements. Discussion: This structured, overview is intended to accelerate decision-making in the medical research community when choosing data platforms. By supporting context-sensitive, feature-weighted selection rather than one-size-fits-all comparisons, it acknowledges diversified research needs and can be updated as technologies and practices evolve.

Indexed as

data harmonizationdata privacyequirement-weighted assessmentFAIR datafederated learningiteroperabilitymedical research data platformstranslational biomedical research

Identifiers

PMID42388293
PMCPMC13319098

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.