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ArticleFrontiers in neurology

Clinical and CT angiography characteristics of Chinese stroke patients with carotid web: a retrospective study.

Zhuoman Chen, Jingjing Cai, Xianfu Hu, Jiaming Huang, Yougang Ke, Jing Hu, Siping Luo, Lijie Ren

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Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Zhuoman ChenDepartment of General Practice, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
Jingjing CaiDepartment of Neurology, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
Xianfu HuDepartment of Gastroenterology, The People's Hospital of Longhua, Shenzhen, Guangdong, China.
Jiaming HuangDepartment of Rheumatology and Immunology, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
Yougang KeDepartment of Radiology, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong, China.
Jing HuDepartment of General Practice, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong, China.
Siping LuoDepartment of Radiology, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
Lijie RenDepartment of Neurology, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carotid web (CaW) is a recognized risk factor for ischemic stroke, histopathologically classified as intimal fibromuscular dysplasia. However, clinical and imaging characteristics of CaW may vary across ethnic populations, and data from the Chinese population remain limited. This study aimed to investigate the clinical and computed tomography angiography (CTA) characteristics of CaW in Chinese stroke patients. Methods: We retrospectively reviewed CTA examinations of 9,220 patients at a single center in southern China from November 2005 to February 2021. Patients with CaW diagnosed on CTA were identified. Demographic data, clinical presentations, comorbidities, and CTA features including location, orientation, lumen dimensions, and stenosis severity were analyzed. Comparisons between cerebral infarction and non-cerebral infarction groups were performed using independent-sample Results: A total of 34 patients (32 males, 2 females; mean age 56.97 ± 14.75 years) with 42 CaWs were identified (prevalence 0.37%). The majority of CaWs (37/42, 88.1%) were located at the common carotid artery (CCA) bifurcation, with 5 (11.9%) at the internal carotid artery (ICA) bulb. Unilateral CaW was found in 26 patients (76.5%) and bilateral in 8 (23.5%). Cerebral infarction was the most common diagnosis (21/34, 61.8%). The lumen diameter at the CaW site was significantly different between the cerebral infarction and non-infarction groups (8.97 ± 2.34 mm vs. 6.80 ± 1.90 mm, Conclusions: In the Chinese population, CaW predominantly affects males and tends to be unilateral, located at the CCA bifurcation. CaW-induced mild carotid stenosis constituted the majority of cases. CaW is an important risk factor for cryptogenic cerebral infarction. The lumen diameter at CaW sites and hypertension were significantly associated with cerebral infarction, highlighting the need for careful CTA evaluation and individualized management strategies.

Indexed as

carotid webcerebral infarctionChinese populationcomputed tomography angiographyfibromuscular dysplasiaischemic stroke

Identifiers

PMID42388700
PMCPMC13318593

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.