ArticleBlood red cells & iron2025
Resolution of inflammation increases erythropoiesis.
Kim Uyen C Nguyen, Carol K Cox, Daniel Stephenson, Angelo D'Alessandro, Luciano D Mendoza, Erin B Taylor, Jerry D Monroe, Yann Gibert
Abstract read
In one paragraphArticle in Blood red cells & iron, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Kim Uyen C NguyenDepartment of Cell and Molecular Biology, Cancer Center and Research Institute, University of Mississippi Medical Center, Jackson, MS.
Carol K CoxDepartment of Cell and Molecular Biology, Cancer Center and Research Institute, University of Mississippi Medical Center, Jackson, MS.
Daniel StephensonDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO.
Angelo D'AlessandroDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO.ORCID 0000-0002-2258-6490 Luciano D MendozaDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS.
Erin B TaylorDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS.ORCID 0000-0003-0122-0833 Jerry D MonroeDepartment of Cell and Molecular Biology, Cancer Center and Research Institute, University of Mississippi Medical Center, Jackson, MS.
Yann GibertDepartment of Cell and Molecular Biology, Cancer Center and Research Institute, University of Mississippi Medical Center, Jackson, MS.ORCID 0000-0001-8208-7223 Funding
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Pier Paolo Claudio, Babbette LaMarca · 2017 to 2026
$26.4MThe role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI ALEXANDER, BARBARA T · 2013 to 2022
$23.4MThe Impact of Obesity and Leptin on the Development of Immune System Dysfunction and Hypertension in Females with Systemic Lupus ErythematousU54HL169191 · NHLBI · AUGUSTA UNIVERSITY · PI Daria Ilatovskaya · 2023 to 2026
$7.4MPilot Projects ProgramP30GM149404 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI John E Hall · 2023 to 2026
$6.3MThe role of ferroptosis in red cell aging in vivo and in vitroR01HL146442 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Angelo D'Alessandro, Adam N. Goldfarb · 2019 to 2026
$5.4MInteractions between the ADORA2b/Sphk1axis and the AE1-Hb switch in red blood cell aging in vivo and in vitroR01HL149714 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI D'ALESSANDRO, ANGELO · 2020 to 2023
$2.6MImmune system dysfunction and gut dysbiosis in the pathogenesis of vascular dysfunction in autoimmunityR00HL146888 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2022 to 2024
$747kRoles of DPA derived specialized pre-resolving mediators during vertebrate hematopoiesisF31HL170707 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI NGUYEN, KIM UYEN · 2023 to 2024
$65kNHLBI NIH HHS F31 HL170707NHLBI NIH HHS R00 HL146888NHLBI NIH HHS R01 HL146442NHLBI NIH HHS R01 HL149714NHLBI NIH HHS U54 HL169191NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334NIGMS NIH HHS P30 GM149404
6 · The paper itselfAbstract
Erythropoiesis is a vital process for blood production, and its disruption contributes to various forms of anemia. In this study, we investigated the hematopoietic effects of bioactive lipid mediators derived from n-3 polyunsaturated fatty acids (n-3 PUFAs), focusing on a class of compounds known as specialized proresolving mediators (SPMs) that promote inflammation resolution. Using zebrafish embryos, we screened several n-3 PUFA-derived SPMs and identified 7(S),17(S)-dihydroxydocosapentaenoic acid (7,17-diHDPAn-3) that significantly enhances erythropoiesis. Exposure to 7,17-diHDPAn-3 upregulated
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PMID42389190
PMCPMC13322275
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