Evidence map›Paper›PMID 42389254›Full record

ReviewCureus2026

A Narrative Review of the Potential Impact of Next-Generation Tobacco and Nicotine Products on Cardiovascular Health.

Ian M Fearon, Matthew Stevenson, Thomas Nahde

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ian M FearonScientific Research, whatIF? Consulting Ltd, Harwell, GBR.
Matthew StevensonGroup Science and Regulatory Affairs, Imperial Brands PLC, Bristol, GBR.
Thomas NahdeGroup Science and Regulatory Affairs, Reemstma Cigarettenfabriken GmbH, Hamburg, DEU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigarette smoking is a cause of serious disease in smokers, including cardiovascular disease (CVD). The processes underpinning the development of CVD are well understood. These involve many cell types and cellular processes contributing to the development of atherosclerotic plaques in blood vessels, leading to impaired tissue oxygen supply and acute manifestations such as myocardial infarction and stroke. Cigarette smoke contains thousands of chemicals, some of which can be harmful to the cardiovascular system and may promote atherogenesis. In this narrative review, we assess the growing body of evidence concerning the potential cardiovascular health impact of next‑generation tobacco and nicotine product (NGP) use, including electronic vaping product (EVP), heated tobacco product (HTP) and oral nicotine pouch (ONP) use. Exclusive use of NGPs substantially reduces exposure to harmful toxicants compared with cigarette smoking. Regarding CVD risk, we determine that: (i) in vivo and in vitro

Indexed as

cardiovascular diseasecigarette smokingelectronic vaping productsheated tobacco productsnicotine pouchestobacco harm reduction

Identifiers

PMID42389254
PMCPMC13320579

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.