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ArticleDigital health

Large language model chatbots as sources of pediatric anesthesia health advice: An evaluation of reliability and readability.

Xue Zhang, Yuchen Dai, Xin Zhao, Lin Wu, Boming Shao, Xisheng Shan, Fuhai Ji, Runzhi Deng, Baojian Zhao

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Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xue ZhangDepartment of Anesthesiology, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing Stomatological Hospital, Nanjing, Jiangsu, China.
Yuchen DaiDepartment of Anesthesiology, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing Stomatological Hospital, Nanjing, Jiangsu, China.
Xin ZhaoDepartment of Anesthesiology, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing Stomatological Hospital, Nanjing, Jiangsu, China.
Lin WuDepartment of Anesthesiology, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing Stomatological Hospital, Nanjing, Jiangsu, China.
Boming ShaoDepartment of Anesthesiology, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing Stomatological Hospital, Nanjing, Jiangsu, China.
Xisheng ShanDepartment of Anesthesiology, Institute of Anesthesiology, Soochow University, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Fuhai JiDepartment of Anesthesiology, Institute of Anesthesiology, Soochow University, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Runzhi DengDepartment of Oral and Maxillofacial Surgery, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing Stomatological Hospital, Nanjing, Jiangsu, China.
Baojian ZhaoDepartment of Anesthesiology, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing Stomatological Hospital, Nanjing, Jiangsu, China.ORCID https://orcid.org/0009-0000-8934-3146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Large language models are increasingly used to obtain health information, but their quality in pediatric anesthesia remains insufficiently evaluated. This study aimed to assess the reliability and readability of four widely used AI chatbots in this context. Methods: This cross-sectional observational study developed 18 pediatric anesthesia-related questions using Medical Subject Headings terms, online search trend analysis, and commonly queried topics reflecting parental information needs. Each question was submitted under standardized conditions to four generative AI-driven chatbots: OpenAI's GPT-5.1 Thinking, Google's Gemini 3 Pro, Anthropic's Claude Opus 4.5 Extended Thinking, and DeepSeek-V3.2-Speciale. Models were accessed in their vendor-deployed configurations without task-specific fine-tuning. The generated responses were evaluated for information reliability using the Ensuring Quality Information for Patients (EQIP) instrument, DISCERN tool, Global Quality Score (GQS), and Journal of the American Medical Association (JAMA) benchmark criteria. Readability was assessed using seven validated indices including Flesch Reading Ease Score, Flesch-Kincaid Grade Level, Gunning Fog Index, Simple Measure of Gobbledygook, Coleman-Liau Index, Automated Readability Index, and Linsear Write Formula. Results: A total of 72 chatbot-generated responses were included for analysis. Significant between-model differences were observed in DISCERN, EQIP, and GQS, while JAMA benchmark scores were consistently low across all models. DeepSeek and Gemini showed higher median reliability scores across several instruments, although significant pairwise differences mainly involved ChatGPT. None of the evaluated models achieved the recommended sixth-grade readability level across any index. Correlations between reliability and readability were non-significant, suggesting that these represent independent dimensions of information quality. Conclusions: Current LLM-based chatbots provided pediatric anesthesia information with variable reliability and consistently suboptimal readability. Although certain models demonstrated relatively higher information quality, limited transparency and excessive reading complexity may restrict their suitability for public-facing educational use. These findings highlight the need for improved quality control, enhanced transparency, and readability-focused optimization in pediatric perioperative education.

Indexed as

digital health informationgenerative artificial intelligencelarge language modelspediatric anesthesiareadability

Identifiers

PMID42389384
PMCPMC13319765

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.