ArticleFrontiers in bioengineering and biotechnology2026
Engineering
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Lactic acid bacteria are commonly used to convert carbohydrates into valuable products like lactic acid, but they currently rely on carbon sources from food crops, raising sustainability and cost concerns. Lignocellulosic waste is a more sustainable alternative, yet these bacteria cannot naturally break down cellulose to grow on it. Efficient cellulose degradation requires synergetic action of multiple cellulolytic enzymes, each operating through distinct mechanisms. Methods: To design genetic constructs for co-expression of gene pairs encoding different heterologous cellulases (Cel5I, Cel5H or Cel9A) from separate expression cassettes in Results: The A1 strain that co-produced cellulase pair Cel5H-Cel9A achieved the highest activity on PASC and one of the highest activities measured on microcrystalline cellulose. Additionally, the A1 strain showed the highest degradation of PASC during the 16 days of anaerobic cultivation and one of the highest lactic acid production levels. Discussion: In this study, co-expression of gene pairs that encode different heterologous cellulases from separate promoters in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.