Evidence mapPaperPMID 42389488Full record

ReviewJournal of pharmaceutical analysis2026

Principles and strategies in cold/hot property studies of traditional Chinese medicine: an evolution from traditional theory to modern elucidation.

Min Zhang, Xin Zhang, Rui Wei, Yi-Nuo Li, Ying Hu, Ya-Dan Zou, Xue Li, Yue-Fei Wang, Wen-Zhi Yang, De-An Guo

Abstract readReview
In one paragraph

Review in Journal of pharmaceutical analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min ZhangState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Xin ZhangState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Rui WeiState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yi-Nuo LiState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Ying HuState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Ya-Dan ZouState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Xue LiState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yue-Fei WangState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Wen-Zhi YangState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
De-An GuoState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Property of traditional Chinese medicine (TCM) is the core of the basic theories of TCM. Especially, the cold and hot properties are considered as closely related to the clinical medication and have the guiding significance. Driven by the ongoing advances of modern analytical technology, studies on the ancient theory of TCM cold and hot properties are flourishing recently; however, the review focusing on the applied research methods is insufficient. This review, by the bibliometric analysis of 996 associated publications, discloses the methodological evolution in researching the cold and hot properties of TCM from the traditional temperature-based methods (e.g., cold/hot plate differentiating and infrared thermography technologies) to modern elucidation that relies on the material basis-oriented strategies (multi-omics and gut microbiomics). The analytical techniques that are appliable to the

Indexed as

BiothermodynamicsCold and hot propertyMachine learningMulti-omicsTraditional Chinese medicine

Identifiers

PMID42389488
PMCPMC13321016

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.