Evidence mapPaperPMID 42389492Full record

ReviewBiotechnology notes (Amsterdam, Netherlands)2026

Probiotics, postbiotics, and synbiotics in immune system modulation: A narrative review.

Mina Owrang

Abstract readReview
In one paragraph

Review in Biotechnology notes (Amsterdam, Netherlands), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mina OwrangDepartment of Medical Laboratory Sciences, Faculty of Medical Sciences, Sari.C., Islamic Azad University, Sari, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interactions between the intestinal microbiota and the immune system play a crucial role in human health and the pathogenesis of various diseases. Since many beneficial effects of probiotics are mediated through their bioactive metabolites, increasing attention has been directed toward postbiotics and synbiotics as potential alternatives or complementary microbiota-based interventions. This review summarizes current evidence regarding the interactions and immunomodulatory effects of probiotics, postbiotics, and synbiotics on the human immune system. Although the immunomodulatory effects of probiotics have been extensively investigated, evidence regarding synbiotics and postbiotics remains comparatively limited and continues to evolve. A deeper understanding of the interactions between microbiota-derived bioactives and the immune system may contribute to the development of novel therapeutic strategies. This study was conducted as a narrative review based on a qualitative synthesis of the currently available literature.

Indexed as

Immune systemMicrobiotaPostbioticProbioticSynbioti

Identifiers

PMID42389492
PMCPMC13320421

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.