Evidence mapPaperPMID 42390201Full record

ArticleACS chemical biology2026

Inositol Thiophosphates as Inhibitors of Mammalian, Plant, and Fungal Phytases.

Seyed Ehsan Vasegh, Rebecca Cummer, Justin Meneses, Lie Von Kok, Lauren M Finn, Valentin Nelea, Lharbi Dridi, Bettina G Keller, Dieter P Reinhardt, Bastien Castagner

Abstract read
In one paragraph

Article in ACS chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seyed Ehsan VaseghDepartment of Pharmacology and Therapeutics, McGill University, 3655 Prom. Sir-William-Osler, Montreal, Quebec H3G 1Y6, Canada.ORCID 0009-0008-0217-1635
Rebecca CummerDepartment of Pharmacology and Therapeutics, McGill University, 3655 Prom. Sir-William-Osler, Montreal, Quebec H3G 1Y6, Canada.ORCID 0009-0009-9336-0737
Justin MenesesDepartment of Pharmacology and Therapeutics, McGill University, 3655 Prom. Sir-William-Osler, Montreal, Quebec H3G 1Y6, Canada.
Lie Von KokDepartment of Pharmacology and Therapeutics, McGill University, 3655 Prom. Sir-William-Osler, Montreal, Quebec H3G 1Y6, Canada.
Lauren M FinnDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Arnimallee 22, Berlin 14195, Germany.ORCID 0009-0009-0947-5217
Valentin NeleaFaculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Quebec H3A 0C7, Canada.
Lharbi DridiDepartment of Pharmacology and Therapeutics, McGill University, 3655 Prom. Sir-William-Osler, Montreal, Quebec H3G 1Y6, Canada.
Bettina G KellerDepartment of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Arnimallee 22, Berlin 14195, Germany.ORCID 0000-0002-7051-0888
Dieter P ReinhardtFaculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Quebec H3A 0C7, Canada.
Bastien CastagnerDepartment of Pharmacology and Therapeutics, McGill University, 3655 Prom. Sir-William-Osler, Montreal, Quebec H3G 1Y6, Canada.ORCID 0000-0002-9207-1329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inositol phosphates constitute a conserved family of signaling molecules that regulate a wide range of cellular processes such as energy metabolism, calcium release, and signal transduction. In mammalian cells, the endoplasmic reticulum-localized enzyme, multiple inositol polyphosphate phosphatase 1 (MINPP1), is the sole phytase known to hydrolyze

Indexed as

6-PhytaseEnzyme InhibitorsInositol PhosphatesAnimalsFungiPhosphoric Monoester Hydrolases6-PhytaseEnzyme InhibitorsInositol PhosphatesPhosphoric Monoester Hydrolases

Identifiers

PMID42390201
PMCPMC13386463

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.