ArticleEuropean journal of applied physiology2026
Does creatine supplementation improve strength and power in physically active individuals on a vegan diet? a randomized, triple-blind, placebo-controlled trial.
Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06483321 (Effect of Creatine Supplementation on Physical Performance and Body Composition in Vegan Subjects), which is not on this map. Not yet cited in PubMed.
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Effect of Creatine Supplementation on Physical Performance and Body Composition in Vegan Subjects
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9 authors.
Funding
Abstract
purposeThis study aimed to assess the impact of four weeks of creatine monohydrate supplementation on strength and power performance in physically active individuals following a vegan diet.
methodsTwenty physically active vegan adults (18-45 years) were enrolled in a triple-blind, placebo-controlled study. Participants were randomly assigned to receive either creatine monohydrate (0.1 g·kg⁻¹·day⁻¹; 5 females and 5 males) or a placebo (5 females and 5 males), while adhering to a normocaloric vegan diet. Body composition, physical performance (countermovement jump test (CMJ), sprint, repeated jumps, handgrip strength, and isometric mid-thigh pull), and renal biomarkers were assessed at baseline and after a 4-week supplementation period.
resultsAfter 4 weeks, the creatine group showed significant increases in skeletal muscle mass (+ 0.3 kg), total body water (+ 1.4 kg), and BMI (+ 0.3 kg/m²), along with reduced body fat (-1.4 kg) compared to controls (p < 0.05). Serum creatinine and creatine levels significantly increased in the creatine group (p < 0.001-0.03). Performance improvements were observed in lower-body explosive performance, particularly in CMJ, as well as in maximal height and flight time during repeated jumps (p < 0.001-0.04), with no changes in sprint or strength tests.
conclusionFour weeks of creatine supplementation in individuals following a vegan diet enhances muscle strength and lower-body muscular power. Longer-term studies are needed to confirm the effectiveness and safety of creatine supplementation in this population.
trial registrationNCT06483321. https//clinicaltrials.gov/study/NCT06483321.
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