Evidence map›Paper›PMID 42391285›Full record

ArticleMicrobiology (Reading, England)2026

Commonly prescribed medicines antagonise anti-MRSA antibiotics and select for resistance.

Zoha Sohail, Henry A Claireaux, Andrew M Edwards, Edward J A Douglas

Abstract read
In one paragraph

Article in Microbiology (Reading, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zoha SohailCentre for Bacterial Resistance Biology, Imperial College London, London SW7 2AY, UK.
Henry A ClaireauxCentre for Bacterial Resistance Biology, Imperial College London, London SW7 2AY, UK.
Andrew M EdwardsCentre for Bacterial Resistance Biology, Imperial College London, London SW7 2AY, UK.
Edward J A DouglasCentre for Bacterial Resistance Biology, Imperial College London, London SW7 2AY, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many commonly prescribed non-antibiotic medicines have off-target antimicrobial activity, yet their impact on antibiotic efficacy remains poorly understood. In this study, we investigated eight widely used UK prescription medicines and identified simvastatin, amlodipine and fluoxetine as growth inhibitory towards methicillin-resistant

Indexed as

Anti-Bacterial AgentsMethicillin-Resistant Staphylococcus aureusCell WallDrug AntagonismDrug Resistance, BacterialDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsStaphylococcal InfectionsAnti-Bacterial Agentsantimicrobial resistancepolypharmacyprescription medicinesStaphylococcus aureus

Identifiers

PMID42391285
PMCPMC13327645

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.