Serum Biomarkers in Paediatric Neurosurgery: Traumatic Brain Injury and Beyond.

Benjamin J Hall, Simon Abrams, Michael J Griffiths, Kristian Aquilina, Conor Mallucci

Abstract read

In one paragraph

Article in Advances and technical standards in neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin J HallDepartment of Neurosurgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.

Simon AbramsInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.

Michael J GriffithsCentre of Child and Adolescent Health Research, University of Sydney, Sydney, Australia.

Kristian AquilinaDepartment of Neurosurgery, Great Ormond Street Hospital, London, UK. Kristian.aquilina@gosh.nhs.uk.

Conor MallucciDepartment of Neurosurgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the leading cause of disability and death in children, paediatric traumatic brain injury (pTBI) is a clinical concern that impacts children on a global scale [1]. The incidence of TBI varies dramatically both between and within countries, ranging between 47 and 280 per 100,000 children, and is generally more common in males [1]. All ages are affected by TBI throughout childhood, though typically two peaks during infancy (0-2 years) and adolescence (15-18 years) are the most common intervals [1]. Mild TBIs (mTBIs) are the most frequently diagnosed, accounting for between 75 and 90% of cases, with a vast majority demonstrating no pertinent radiological findings and discharged home without follow-up.

Indexed as

BiomarkersBrain Injuries, TraumaticAdolescentChildChild, PreschoolFemaleHumansInfantMaleBiomarkers

Identifiers

PMID42393441

DOI10.1016/j.wneu.2023.02.102

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.