L-Ornithine-L-aspartate enhances growth performance and nitrogen metabolism via modulation of intestinal amino acid transporters and microbiota in broilers.

Xiaodan Zhang, Guangzhi Ma, Jinping Wang, Bin Wang, Zengpeng Lv, Yuming Guo

Abstract read

In one paragraph

Article in Journal of animal science and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaodan ZhangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.

Guangzhi MaAnhui Wanhe Jial Biotechnology Co., Ltd., Anhui, 239000, China.

Jinping WangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.

Bin WangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.

Zengpeng LvState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.

Yuming GuoState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. guoyum@cau.edu.cn.

Funding

China Agriculture Research System CARS-41-G04

6 · The paper itself

Abstract

backgroundL-Ornithine-L-aspartate (OA) is a stable salt formed by the ionic bonding of ornithine and aspartic acid. While OA is known to regulate nitrogen metabolism and ammonia (NH

resultsCompared to the basal diet, both supplementation groups improved growth performance and slaughter performance by promoting glutamine (Gln) synthesis and NH

conclusionsIn summary, while both forms are beneficial, OA is superior to the physical mixture of ornithine and aspartic acid in improving broiler performance. This advantage of the OA was correlated with the up-regulated intestinal AA transporters, improved the digestibility of nutrients such as ornithine, and the modulated gut microbiota towards a butyrate-producing profile, coupled with increased hepatic OAT activity.

Indexed as

AA-targeted metabolomicsBroilersL-Ornithine-L-aspartateMicrobiotaMulti-omics analysisNitrogen metabolism

Identifiers

PMID42393821

DOI10.1186/s40104-026-01450-7

PMCPMC13330389

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.